A comparison between 40 MHz intravascular ultrasound iMap imaging system and integrated backscatter intravascular ultrasound
A comparison between 40 MHz intravascular ultrasound iMap imaging system and integrated backscatter intravascular ultrasound
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DOI：
10.1016/j.jjcc.2012.10.008
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发表时间：
2013-01-01
影响因子：
2.5
通讯作者：
Yoshida, Kiyoshi
中科院分区：
文献类型：
--
作者：
Yamada, Ryotaro;Okura, Hiroyuki;Yoshida, Kiyoshi
背景：Map是一种基于射频（RF）信号模式识别的血管内超声（IVUS）组织表征系统。目的：本研究的目的是比较iMap和另一种先前验证过的组织表征系统，integrated backscatter (IB)-IVUS的组织表征，并澄清这两种方法之间的异同。方法：对16例缺血性心脏病患者31个病灶进行研究。采用40 MHz IVUS导管进行IVUS成像。然后输出来自每个病变的射频信号，使用iMap和IB-IVUS分析组织特征。iMap将冠状动脉斑块分为纤维化、脂质化、坏死和钙化四类。IB-IVUS将冠状动脉斑块分为纤维化、脂质池、致密纤维化和钙化四类。在获得图像后，在完全相同的横截面上比较IB-IVUS和iMap图像。由于严重钙化是一种完美的反射，因此排除了致密钙化病变（>20%）。结果：iMap法纤维化和钙化与IB-IVUS法纤维化和钙化相关性良好(纤维化vs纤维化：r（2) = 0.522, p < 0.001，钙化vs钙化：r(2) = 0.560, p < 0.001）。iMap的脂质化与IB-IVUS的脂质池不相关，但iMap的坏死与IB-IVUS的脂质池相关性良好（r(2) = 0.480, p < 0.001）。结论：iMap分类的组织类型与IB-IVUS分类的组织类型相关性较好，但两者之间存在一定差异。这些结果可能需要仔细解释不同IVUS组织表征系统获得的组织类型。(C) 2012年日本心脏病学会。Elsevier Ltd.出版。版权所有。
Background: Map is a newly developed intravascular ultrasound (IVUS) tissue characterization system based on pattern recognition of the radio frequency (RF) signals.Purpose: The purpose of this study was to compare tissue characterization between iMap and another previously validated tissue characterization system, integrated backscatter (IB)-IVUS in vivo and to clarify similarities and differences between these two methods.Methods: A total of 31 lesions from 16 patients with ischemic heart disease were studied. IVUS imaging was performed using 40 MHz IVUS catheter. RF signals from each lesion were then exported to analyze tissue characterization using both iMap and IB-IVUS. By iMap, coronary plaque was classified into four categories, fibrotic, lipidic, necrotic, or calcified. By IB-IVUS, coronary plaque was classified into four categories, fibrosis, lipid pool, dense fibrosis, or calcification. After the images were acquired, IB-IVUS and iMap images were compared at exactly the same cross-sections. Because severe calcification is a perfect reflector, dense calcification lesions (>20%) were excluded.Results: Both fibrotic and calcified by iMap correlated well with fibrosis and calcification by IB-IVUS (fibrotic vs. fibrosis: r(2) = 0.522, p < 0.001, calcified vs. calcification: r(2) = 0.560, p < 0.001). Although lipidic by iMap did not correlate with lipid pool by IB-IVUS, necrotic by iMap correlated well with lipid pool by IB-IVUS (r(2) = 0.480, p < 0.001).Conclusion: Although tissue types classified by iMap correlated well with corresponding tissue type by IB-IVUS, some discrepancy presented between the two systems. These results may call for careful interpretation of the tissue types obtained by the different IVUS tissue characterization systems. (C) 2012 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.