Design, synthesis and in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antitubercular and antimalarial agents
Design, synthesis and in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antitubercular and antimalarial agents
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DOI：
10.1016/j.cclet.2012.05.004
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发表时间：
2012-07-01
影响因子：
9.1
通讯作者：
Raval, Jignesh Priyakant
中科院分区：
文献类型：
--
作者：
Akhaja, Tarunkumar Nanjibhai;Raval, Jignesh Priyakant
合成了一系列5-取代-3-[{5-（6-甲基-2-氧/硫代-4-苯基-1，2，3，4-四氢嘧啶-5-基）-1，3，4-恶二唑-2-基）-亚氨基]-1，3-二氢-2H-吲哚-2-酮，并对其进行了结构表征和抗结核、抗疟活性筛选。(C)2012年Jignesh Priyakant Raval。Elsevier B. V.代表中国化学会出版。All rights reserved.
A series of 5-substituted-3-[{5-(6-methyl-2-oxo/thioxo-4-phenyl-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-oxadiazol-2-yl)-imino]-1,3-dihydro-2H-indol-2-one were synthesized, characterized and screened for their anti-tubercular and antimalarial activity. (C) 2012 Jignesh Priyakant Raval. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.