Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors.
Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors.
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DOI：
10.1016/j.drudis.2018.11.012
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发表时间：
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通讯作者：
PengZhan
中科院分区：
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作者：
LanlanJing;GaochanWu;DongweiKang;ZhongxiaZhou;YuningSong;XinyongLiu;PengZhan
Butyrylcholinesterase (BChE) is considered a promising drug target for the treatment of moderate to severe Alzheimer's disease (AD). Here, we review medicinal-chemistry strategies that are currently available for the discovery of selective BChE inhibitors.
