Synthetic Strategies Towards the Meroterpenoids Cochlearols A and B from Ganoderma Cochlear
Synthetic Strategies Towards the Meroterpenoids Cochlearols A and B from Ganoderma Cochlear
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灵芝耳蜗中类萜类耳蜗醇A和B的合成策略
DOI：
10.1055/a-1878-7795
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Vogel, Trenton R
中科院分区：
文献类型：
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作者：
Schindler, Corinna S;Chamness, Stephen A;Traficante, Emily F;Vogel, Trenton R
自首次报道其分离以来，部分萜类化合物cochlearol A和B因其独特的结构特征而引起了合成界的兴趣。本文综述了这些天然产物的尝试和成功的全合成，并提供了自其分离以来的几年中开发的策略的总结。1引言2 Cochlearol A合成概述3 Tong的Cochlearol A4 Liu和Qin的全合成（±）-Cochlearol A5 Ishigami的（±）-Cochlearol A6的形式合成（±）-Coch Cochlearol A7 Sugita合成（±）-Cochlearol B8 Schindler合成（+）-Cochlearol B 9结论
Since the first reports of their isolation, the meroterpenoids cochlearol A and B have attracted interest from the synthetic community for their unique structural features. This review describes the attempted and successful total syntheses of these natural products and provides a summary of the strategies developed in the years since their isolation.1 Introduction2 Overview of Cochlearol A Syntheses3 Tong’s Approach Towards Cochlearol A4 Liu and Qin’s Total Synthesis of (±)-Cochlearol A5 Ishigami’s Formal Synthesis of (±)-Cochlearol A6 Chandrasekhar’s Formal Synthesis of (±)-Cochlearol A7 Sugita’s Synthesis of (±)-Cochlearol B8 Schindler’s Synthesis of (+)-Cochlearol B9 Conclusions