Oxidative cleavage of vic-diols to aldehydes with dioxygen catalyzed by Ru(PPh3)3Cl2 on active carbon.
Oxidative cleavage of vic-diols to aldehydes with dioxygen catalyzed by Ru(PPh3)3Cl2 on active carbon.
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DOI：
10.1021/ol990117w
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发表时间：
1999-08
期刊：
影响因子：
5.2
通讯作者：
E. Takezawa;S. Sakaguchi;Y. Ishii
中科院分区：
文献类型：
--
作者：
E. Takezawa;S. Sakaguchi;Y. Ishii
[反应：见正文]在Ru(PPh_3)_3Cl2的催化下，各种Vic-diol首先被成功地用氧气在活性碳上裂解成相应的醛，产率中等到很好。例如，在Ru(PPh3)3Cl2/C存在下，1，2-辛醇和1，2-环辛醇在PhCF3中于60℃下与氧气反应15 h，得到庚醛和1，8-辛二醛，产率分别为77%和76%。
[reaction: see text] A variety of vic-diols were first successfully cleaved to the corresponding aldehydes with dioxygen catalyzed by Ru(PPh3)3Cl2 on active carbon in fair to good yields. For example, treatment of 1,2-octandiol and 1,2-cyclooctanediol with dioxygen in the presence of Ru(PPh3)3Cl2/C in PhCF3 at 60 degrees C for 15 h produced heptanal and 1,8-octanedial in 77% and 76% yields, respectively.