FDG positron emission tomography in the diagnosis of peripheral pulmonary focal lesions.
FDG positron emission tomography in the diagnosis of peripheral pulmonary focal lesions.
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DOI：
10.1055/s-2000-9875
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发表时间：
2000-04
期刊：
影响因子：
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通讯作者：
G. Halter;M. Storck;A. Guhlmann;J. Frank;S. Grosse;F. Liewald
中科院分区：
文献类型：
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作者：
G. Halter;M. Storck;A. Guhlmann;J. Frank;S. Grosse;F. Liewald
正电子发射断层扫描（PET）使用氟-18-标记的氟脱氧葡萄糖（FDG）是一种代谢为基础的成像技术，能够提供信息的潜在恶性外周肺局灶性病变。在本前瞻性研究中，我们调查了FDG-PET在确定35例患者的67个此类病变的尊严方面的有效性。将FDG-PET的结果与计算机断层扫描（CT）以及手术和组织学报告进行比较，并评估FDG-PET作为诊断方法的价值。FDG-PET正确识别了38个病变为恶性肿瘤阳性，18个正确为阴性，7个错误为阴性，4个错误为阳性。基于病变，这产生了84.4%的灵敏度和81.8%的特异性。所有直径超过1.2 cm的恶性局灶性病变均被正确识别（灵敏度：100%）。在FDG摄取强烈的情况下，原发性病变、转移和急性炎症之间的区分通常是不可能的。
Positron emission tomography (PET) using fluoride-18-marked fluoride deoxyglucose (FDG) represents a metabolically based imaging technique capable of providing information on the potential malignancy of peripheral pulmonary focal lesions. In the present prospective study, we investigated the effectiveness of FDG-PET in determining the dignities of 67 such lesions in 35 patients. Findings of FDG-PET were compared with those of computed tomography (CT), as well as with surgical and histological reports, and the value of FDG-PET as a diagnostic method evaluated. FDG-PET correctly identified 38 lesions as positive for malignancy, 18 correctly as negative, 7 incorrectly as negative, and 4 incorrectly as positive. Based on lesions, this yields a sensitivity of 84.4% and a specificity of 81.8%. All malignant focal lesions with a diameter of over 1.2 cm were correctly identified (sensitivity: 100%). In cases of intense FDG uptake, differentiation between a primary lesion, a metastasis, and an acute inflammation is often not possible.