SALIVARY FLOW, SALIVA, PH AND BUFFERING CAPACITY IN 70-YEAR-OLD MEN AND WOMEN - CORRELATION TO DENTAL-HEALTH, DRYNESS IN THE MOUTH, DISEASE AND DRUG-TREATMENT
SALIVARY FLOW, SALIVA, PH AND BUFFERING CAPACITY IN 70-YEAR-OLD MEN AND WOMEN - CORRELATION TO DENTAL-HEALTH, DRYNESS IN THE MOUTH, DISEASE AND DRUG-TREATMENT
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DOI：
10.1111/j.1365-2842.1984.tb00565.x
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发表时间：
1984-01-01
影响因子：
2.9
通讯作者：
HEDEGARD, B
中科院分区：
文献类型：
--
作者：
OSTERBERG, T;LANDAHL, S;HEDEGARD, B
在哥德堡[瑞典]，一个有代表性的系统选择了30%的70岁老年人（1148人），他们被邀请参加一项人口研究。参与率为85%。16%的男性和25%的女性报告口腔干燥（性别差异）。P < 0.01）。受试者服用的药物数量与主观干燥度之间存在显著相关性（男女均P < 0.001）。服用抗胆碱能药物、抗组胺药、镇静剂、催眠药或吩噻嗪类药物对口干的预测价值最高（男性P < 0.05，女性P < 0.01）。男性和女性的主观干燥感与可确定的疾病数呈正相关（P < 0.01）。在一个连续的样本（58名男性和53名女性）的唾液流量，直接pH值和缓冲效果进行了研究。非刺激性唾液分泌的平均值男性为0.25 ml/min，女性为0.18 ml/min，刺激性唾液分泌的相应数值为1.65 ml/min和1.04 ml/min（性别差异）。P < 0.01）。自觉干燥的女性非刺激性分泌物显著减少（P < 0.01）。药物治疗后，牙体功能障碍与刺激性分泌呈显著负相关（男性P < 0.05，女性P < 0.01）。唾液分泌物和药物治疗之间只有微弱的关系。仅利尿药物的摄入与刺激分泌呈负相关（P < 0.01）。循环系统疾病与主观干燥感相关（P < 0.01）。
A representative systematic selection of 30% of all 70-yr-olds (1148 persons) in Goteborg [Sweden] were invited to a population study. The participation rate was 85%. Dryness in the mouth was reported by 16% of the men and 25% of the women (sex diff. P < 0.01). There was a significant correlation between the number of drugs consumed by the subjects and subjective dryness (in both sexes P < 0.001). Intake of drugs from the groups of anticholinergics, antihistamines, sedatives, hypnotics or phenothiazines, respectively, seemed to have the highest predicative value for dryness in the mouth (men P < 0.05 and women P < 0.01). There was a positive correlation between subjective dryness and number of definable diseases in both sexes (P < 0.01). In a consecutive sample (58 men and 53 women) a study of salivary flow, direct pH and buffer effect were performed. The mean value of unstimulated salivary secretion was in men 0.25 and in women 0.18 ml/min. Corresponding figures for stimulated secretion was 1.65 and 1.04 ml/min (sex diff. P < 0.01). A significant lower unstimulated secretion was noted in women with subjective dryness (P < 0.01). A negative significant correlation were found between dental invalidity, according to Eichner''s classification, and stimulated secretion when drug treatment was considered (men P < 0.05, women P < 0.01). Only weak relations were noted between salivary secretions and drug treatment. Only intake of drugs with diuretic effect were negatively correlated to stimulated secretion (P < 0.01). Diseases of the circulatory system were correlated to subjective dryness (P < 0.01).