Biomarkers in active surveillance.

Biomarkers in active surveillance.
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DOI:
10.21037/tau.2017.12.26
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发表时间:
2018-03
影响因子:
2
通讯作者:
Tosoian JJ
Tosoian JJ
中科院分区:
医学4区
文献类型:
--
作者:
Loeb S;Tosoian JJ

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积极监测(AS)的使用正在增加可排除风险的前列腺癌。然而,由于目前临床分期的局限性,AS患者的选择仍存在挑战。此外,依赖于连续活检的监测方案是侵入性的,并存在感染等风险。由于这些原因,人们对鉴定可用于改善AS选择和监测的标记物非常感兴趣。本文就AS的血清、尿液和组织标志物的研究进展作一综述。
The use of active surveillance (AS) is increasing for favorable-risk prostate cancer. However, there remain challenges in patient selection for AS, due to the limitations of current clinical staging. In addition, monitoring protocols relying on serial biopsies is invasive and presents risks such as infection. For these reasons, there is substantial interest in identifying markers that can be used to improve AS selection and monitoring. In this article, we review the evidence on serum, urine and tissue markers in AS.
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