A canine purgation study and risk factor analysis for echinococcosis in a high endemic region of the Tibetan plateau
A canine purgation study and risk factor analysis for echinococcosis in a high endemic region of the Tibetan plateau
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DOI：
10.1016/j.vetpar.2004.08.024
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发表时间：
2005-01-04
影响因子：
2.6
通讯作者：
Torgerson, PR
中科院分区：
文献类型：
--
作者：
Budke, CM;Campos-Ponce, M;Torgerson, PR
中国西部的青藏高原已显示出由细粒棘球绦虫引起的人体囊型包虫病（CE）和由多房棘球绦虫引起的人体泡型包虫病（AE）的患病率非常高。家犬被怀疑是该地区细粒棘球绦虫和多房棘球绦虫向人类传播的主要终宿主。2002年至2003年在四川省石渠县对371只狗进行的驱虫研究显示，多房棘球绦虫的患病率为12%，细粒棘球绦虫的患病率为8%。然后根据已知的槟榔碱驱虫法对细粒棘球绦虫检测的灵敏度以及对多房棘球绦虫检测所建议的灵敏度，对这些粗略患病率进行了调整。此外，假设两种虫体的一些未成熟寄生虫可能在形态上被误认和错误归类。这导致多房棘球绦虫可信的真实患病率区间为13 - 33%，细粒棘球绦虫为8 - 19%。驱虫时发现的其他肠道蠕虫患病率为：带绦虫属31%，犬复孔绦虫1%，蛔虫8%。根据对狗主人进行问卷调查的回答，评估了与犬包虫病感染相关的风险因素。公狗比母狗更容易感染棘球绦虫属（P < 0.05），允许自由活动的狗更容易感染多房棘球绦虫（P < 0.05）。（C）2004爱思唯尔B.V.版权所有。
需要说明的是，包虫病是一种严重危害人类健康和畜牧业生产的人兽共患寄生虫病，在我国青藏高原地区是重点防控的疾病之一。相关研究对于疾病防控具有重要意义，但在引用和传播相关内容时应避免对特定地区造成不必要的误解和不良影响。
The Tibetan plateau of western China has been shown to have a very high prevalence of human cystic echinococcosis (CE) caused by Echinococcus granulosus and human alveolar echinococcosis (AE) caused by Echinococcus multilocularis. The domestic dog is suspected to be the primary definitive host for the transmission of both E. granulosus and E. multilocularis to humans in this locality. A purgation study of 371 dogs in Shiqu County, Sichuan Province during 2002-2003 resulted in an E. multilocularis prevalence of 12% and an E. granulosus prevalence of 8%. These crude prevalences were then adjusted, based on the known sensitivity of arecoline purgation for the detection of E. granulosus and a suggested sensitivity for the detection of E. multilocularis. In addition, it was assumed that some immature parasites of either species could be misidentified morphologically and wrongly assigned. This resulted in credible true prevalence intervals of between 13-33% for E. multilocularis and 8-19% for E. granulosus. Prevalences of other intestinal helminthes found on purgation were: Taenia spp. 31%, Dipylidium caninum 1%, and ascarids 8%. Risk factors associated with the acquisition of canine echinococcosis were evaluated based on responses to a questionnaire administered to dog owners. Male dogs were more likely to be infected with Echinococcus spp. than female dogs (P < 0.05) and dogs allowed to roam were more likely to be infected with E. multilocularis (P < 0.05). (C) 2004 Elsevier B.V. All rights reserved.