Early weaning from CPAP to high flow nasal cannula in preterm infants is associated with prolonged oxygen requirement: A randomized controlled trial
Early weaning from CPAP to high flow nasal cannula in preterm infants is associated with prolonged oxygen requirement: A randomized controlled trial
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DOI：
10.1016/j.earlhumdev.2010.12.010
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发表时间：
2011-03-01
影响因子：
2.5
通讯作者：
Aly, Hany
中科院分区：
文献类型：
--
作者：
Abdel-Hady, Hesham;Shouman, Basma;Aly, Hany
目的：探讨早产儿经鼻持续气道正压(NCPAP)或不经鼻插管(NC)撤机的较好方法。设计/方法：随机、开放、对照试验。早产儿出生于孕28周，临床稳定的nCPAP为5cmH2O，FiO(2)和Lt；0.30，持续至少24小时，随机分为2组。无NC组维持nCPAP，直到FiO(2)=0.21持续24小时，然后完全脱机，不暴露于NC。如果他们符合不合格的标准，NCPAP将重新启动。当FiO(2)为NCPAP时，NC组断奶。
Objective: To determine the better approach for weaning preterm infants from nasal continuous positive airway pressure (NCPAP) with or without transitioning to nasal cannula (NC).Design/methods: This is a randomized, open label, controlled trial. Preterm infants born at >= 28 weeks gestation who were clinically stable on NCPAP of 5 cm H2O with FiO(2) < 0.30 for at least 24 h were randomly assigned to one of 2 groups. The no-NC group were kept on NCPAP until they were on FiO(2) = 0.21 for 24 h. and then were weaned off NCPAP completely without any exposure to NC. If they met failing criteria, NCPAP was re-instituted. The NC-group was weaned off NCPAP when FiO(2) was