Habitual sleep variability, mediated by nutrition intake, is associated with abdominal obesity in adolescents.
Habitual sleep variability, mediated by nutrition intake, is associated with abdominal obesity in adolescents.
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DOI：
10.1016/j.sleep.2015.07.028
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发表时间：
2015-12
期刊：
影响因子：
4.8
通讯作者：
Liao D
中科院分区：
文献类型：
--
作者：
He F;Bixler EO;Liao J;Berg A;Imamura Kawasawa Y;Fernandez-Mendoza J;Vgontzas AN;Liao D
探讨青少年习惯性睡眠持续时间（HSD）和习惯性睡眠变异性（HSV）与腹型肥胖和营养素摄入之间的中介关系。我们分析了305名参加宾夕法尼亚州立大学儿童队列随访检查的青少年的数据。连续7个晚上使用体动记录装置来计算HSD和HSV。腹部肥胖通过双能x线吸收测量法进行评估。青少年食物频率问卷被用来获得每日总热量，蛋白质，脂肪和碳水化合物的摄入量。线性回归模型被用来关联HSD和HSV与腹部肥胖，并定性地确定中介因素。通过中介模型对中介效应进行了定量估计。调整主要协变量和HSD后，较高的HSV与腹部肥胖指标显著相关。例如，随着HSV增加1小时，男性/女性脂肪比率和内脏脂肪面积分别增加0.02 cm 2（标准误差= 0.01，p = 0.03）和6.86 cm 2（标准误差= 2.82，p = 0.02）。在HSV校正模型中，HSD与腹部肥胖无关。总热量、脂肪和碳水化合物摄入量是重要的中介因素。例如，HSV和内脏脂肪之间20%的关联可以归因于碳水化合物的摄入。更高的HSV，而不是HSD，与腹部肥胖显著相关，这可以部分解释为青少年热量摄入增加，特别是碳水化合物。这项研究表明，应该更加重视青少年建立和保持规律的睡眠模式。
To investigate habitual sleep duration (HSD) and habitual sleep variability (HSV) in relation to abdominal obesity and nutrient intakes as mediating factors in adolescents. We analyzed data from 305 adolescents who participated in the Penn State Child Cohort follow-up examination. An actigraphy device was used for 7 consecutive nights to calculate HSD and HSV. Abdominal obesity was assessed by dual-energy x-ray absorptiometry. The Youth/Adolescent Food Frequency Questionnaire was used to obtain daily total caloric, protein, fat, and carbohydrates intakes. Linear regression models were used to associate HSD and HSV with abdominal obesity and to qualitatively identify mediating factors. The mediating effect was quantitatively estimated by mediation models. After adjusting for major covariates and HSD, higher HSV was significantly associated with abdominal obesity measures. For example, with 1-hour increase in HSV, android/gynoid fat ratio and visceral fat area increased by 0.02 cm2 (standard error = 0.01, p = 0.03) and 6.86 cm2 (standard error = 2.82, p = 0.02), respectively. HSD was not associated with abdominal obesity in HSV-adjusted models. Total caloric, fat, and carbohydrate intakes were significant mediating factors. For instance, 20% of the association between HSV and visceral fat can be attributed to carbohydrate intake. Higher HSV, not HSD, is significantly associated with abdominal obesity, which can be partially explained by increased caloric intake, especially from carbohydrate, in adolescents. This study suggests that more attention should be paid to establish and maintain regular sleep patterns in adolescents.