Study of chemical selectivity of molecular binary mixed micelles of sodium 10-undecenyl sulfate and sodium N-undecenyl leucinate using linear solvation energy relationships model.
Study of chemical selectivity of molecular binary mixed micelles of sodium 10-undecenyl sulfate and sodium N-undecenyl leucinate using linear solvation energy relationships model.
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使用线性溶剂化能关系模型研究 10-十一碳烯基硫酸钠和 N-十一碳烯基亮氨酸钠分子二元混合胶束的化学选择性。
DOI：
10.1016/j.chroma.2012.03.021
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Akbay,Cevdet
中科院分区：
文献类型：
--
作者：
Ahmed,HamidH;Ahlstrom,DavidM;Arslan,Hakan;Guzel,Mustafa;Akbay,Cevdet
制备了聚十一碳烯基硫酸钠（poly-SUS）、聚十一碳烯基亮氨酸钠（poly-SUL）及其组成不同的5种分子二元混合胶束，并将其用作胶束电动色谱（MEKC）的拟固定相。采用线性溶剂化能关系模型和转移自由能研究了7种表面活性剂体系的保留行为和选择性差异。用系统常数差和回归模型确定了7种苯衍生物类假固定相的选择性差异。空腔形成和分散相互作用（v系统常数）和氢键的酸度（B系统常数）的表面活性剂系统被发现有最显着的选择性和MEKC保留的影响。硫酸酯头基的分子胶束，聚SUS，被发现是更多的氢键酸性比亮氨酸头基的分子胶束，聚SUL。其它系统常数（a、s和e）对苯衍生物的保留和选择性的影响不大。模型截距系数（c系统常数），这是负的所有表面活性剂系统具有异常大的值。除苯酚和苯甲醇外，所研究官能团的转移自由能变化均为负值。伪固定相之间的选择性差异也进行了比较，通过绘制对彼此的log k值，并发现同意与LSER结果。
Poly(sodium 10-undecenyl sulfate) (poly-SUS), poly(sodium N-undecenyl leucinate) (poly-SUL) and their five molecular binary mixed micelles with varied SUS:SUL composition were prepared and used as pseudostationary phases in micellar electrokinetic chromatography (MEKC). Linear solvation energy relationships (LSERs) model and free energy of transfer studies were used to characterize the retention behavior and the selectivity differences among the seven surfactant systems. System constant differences and regression models for varied benzene derivative compounds are used to establish the selectivity differences of the seven pseudostationary phases. The cavity formation and dispersion interaction (the v system constant) and the hydrogen-bonding acidity (the b system constant) of the surfactant systems were found to have the most significant influence on selectivity and MEKC retention. The molecular micelle with sulfate head group, poly-SUS, was found to be more hydrogen-bond acidic than the molecular micelle with leucinate head group, poly-SUL. The other system constants (a, s and e) have modest effect on the retention and selectivity of the benzene derivatives. The model intercept coefficients (c system constants), which are negative for all surfactant systems have unusually large values. The free energy changes of transfer for the functional groups studied have all negative values except phenol and benzyl alcohol. Selectivity differences between pseudostationary phases were also compared by plotting the log k values against each other and were found to agree well with LSER results.