Association of personality traits with polypharmacy among community-dwelling older adults in Japan: a cross-sectional analysis of data from the SONIC study.
Association of personality traits with polypharmacy among community-dwelling older adults in Japan: a cross-sectional analysis of data from the SONIC study.
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DOI：
10.1186/s12877-022-03069-5
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发表时间：
2022-04-28
期刊：
影响因子：
4.1
通讯作者：
Gondo, Yasuyuki
中科院分区：
文献类型：
--
作者：
Yoshida, Yuko;Ishizaki, Tatsuro;Masui, Yukie;Arai, Yasumichi;Inagaki, Hiroki;Ogawa, Madoka;Yasumoto, Saori;Iwasa, Hajime;Kamide, Kei;Rakugi, Hiromi;Ikebe, Kazunori;Gondo, Yasuyuki
多种用药是老年人的一个严重问题，通常与不良后果有关，包括健康问题、生活质量下降和医疗费用增加。虽然人格特质与健康行为和疾病有关，但多种药物对人格特质的影响尚不清楚。因此，我们在社区居住的老年人中研究了人格特质与多重用药的关系。本横断面研究分析了836名年龄在69-71岁的社区老年人的数据，这些老年人参加了日本70岁、80岁和90岁老人与百岁老人的纵向队列研究。多重用药定义为同时服用≥5种药物。使用日文neo -五因素量表（NEO-FFI）评估人格特征。NEO-FFI测量了人格特征的五因素模型，包括“神经质”、“外向性”、“开放性”、“宜人性”和“尽责性”。男性和女性的平均服药次数都是3次。在参与者中，23.9%的男性和28.0%的女性存在多重用药现象。多变量logistic回归分析显示，男性神经质（每增加1点校正优势比[aOR] = 1.078, 95%可信区间[CI] = 1.015 ~ 1.144）和女性外向性（aOR = 0.932, 95% CI = 0.884 ~ 0.983）与多药相关。男性较高的神经质和女性较低的外向性与多药有关。本研究表明，人格特质可能参与了导致多药行为发展的过程。个人性格特征的信息可以帮助医疗专业人员对生活方式相关疾病的药物管理做出决策。
Polypharmacy is a serious concern among older adults and is frequently related to adverse outcomes, including health problems, reduced quality of life, and increased medical expenses. Although personality traits are associated with health behaviors and diseases, the effect of polypharmacy on personality traits is unclear. Therefore, we examined the association of personality traits with polypharmacy among community-dwelling older adults. This cross-sectional study analysed data on 836 community-dwelling older adults aged 69–71 years who participated in the Japanese longitudinal cohort study of Septuagenarians, Octogenarians, and Nonagenarians Investigation with Centenarians. Polypharmacy was defined as the intake of ≥ 5 medications concurrently. Personality traits were assessed using the Japanese version of the NEO-Five-Factor Inventory (NEO-FFI). A five-factor model of personality traits, including “neuroticism,” “extraversion,” “openness,” “agreeableness,” and “conscientiousness,” was measured by the NEO-FFI. The average number of medications was about 3 in both men and women. Among the participants, polypharmacy was observed in 23.9% of men and 28.0% of women. Multivariable logistic regression analysis showed that neuroticism (adjusted odds ratio [aOR] per 1 point increase = 1.078, 95% confidence interval [CI] = 1.015–1.144) in men and extraversion (aOR = 0.932, 95% CI = 0.884–0.983) in women were associated with polypharmacy. Higher neuroticism in men and lower extraversion in women were associated with polypharmacy. This study suggests that personality traits may be involved in the process leading to the development of polypharmacy. Information on individual personality traits may help medical professionals in decision-making regarding medication management for lifestyle-related diseases.
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影响因子：
2.7
作者：
Herbolsheimer, Florian;Ungar, Nadine;Peter, Richard
通讯作者：
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作者：
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影响因子：
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