Two cases of septic shock with different outcomes caused by non-O1/non-O139Vibrio choleraeisolates
Two cases of septic shock with different outcomes caused by non-O1/non-O139Vibrio choleraeisolates
复制标题
两例由非 O1/非 O139 霍乱弧菌分离株引起的败血性休克，结果不同。
DOI：
10.1177/0300060520933459
复制
发表时间：
2020-06-01
影响因子：
1.6
通讯作者：
Min, Xun
中科院分区：
文献类型：
--
作者：
Chen, Jie;Huang, Jian;Min, Xun
近几十年来，越来越多的人感染与非O1/非O139霍乱弧菌有关。由非O1/非O139V引起的败血症。霍乱感染很少见，但死亡率很高。非O1/非O139V的致病机制人们对霍乱败血症知之甚少。在这里，我们报告两个非O1/非O139V后的散发性败血症病例。中国内陆地区的霍乱感染。患者1在24小时内迅速死亡，患者2逐渐从感染性休克中恢复。为了探索这些不同结果的原因，我们比较了这两个病例，测试了两个分离株的抗生素敏感性，并调查了它们的毒力基因和序列类型。
In recent decades, increasing numbers of human infections have been linked to non-O1/non-O139Vibrio cholerae. Septicemia resulting from non-O1/non-O139V. choleraeinfection is rare but has high mortality. The pathogenesis of non-O1/non-O139V. choleraesepticemia is poorly understood. Here, we report two sporadic cases of septicemia following non-O1/non-O139V. choleraeinfection from an inland area of China. Patient 1 died rapidly within 24 hours, while patient 2 gradually recovered from septic shock. To explore the reasons for these divergent outcomes, we compared the two cases, tested the antibiotic sensitivity of the two isolates, and investigated their virulence genes and sequence types.