NERVE LESION IN CARPAL-TUNNEL SYNDROME
NERVE LESION IN CARPAL-TUNNEL SYNDROME
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DOI：
10.1136/jnnp.39.7.615
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发表时间：
1976-01-01
影响因子：
11
通讯作者：
SUNDERLAND, S
中科院分区：
文献类型：
--
作者：
SUNDERLAND, S
压力变形和缺血在压迫性神经病变产生中的相对作用仍然是一个有争议的问题。本文讨论了腕管正中神经受压后结构变化的原因。最初的病变是静脉内缺氧，是由于隧道内压力增加而阻塞静脉回流引起的。这将导致管内水肿和管内压力增加，从而损害并最终破坏神经纤维的血液供应和压迫。最终的结果是纤维组织取代了耻骨囊的内容物。
The relative roles of pressure deformation and ischaemia in the production of compression nerve lesions remain a controversial issue. This paper concerns the genesis of the structural changes which follow compression of the median nerve in the carpal tunnel. The initial lesion is an intrafunicular anoxia caused by obstruction to the venous return from the funiculi as the result of increased pressure in the tunnel. This leads to intrafunicular oedema and an increase in intrafunicular pressure which imperil and finally destroy nerve fibres by impairing their blood supply and by compression. The final outcome is the fibrous tissue replacement of the contents of the funiculi.