Chemical composition and biological activities of whole and dehulled hemp (Cannabis sativa L.) seeds
Chemical composition and biological activities of whole and dehulled hemp (Cannabis sativa L.) seeds
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DOI：
10.1016/j.foodchem.2021.131754
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发表时间：
2021-12-08
期刊：
影响因子：
8.8
通讯作者：
De Cortes Sanchez-Mata, Maria
中科院分区：
文献类型：
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作者：
Alonso-Esteban, Jose Ignacio;Pinela, Jose;De Cortes Sanchez-Mata, Maria
本研究的目的是确定一个完整的化学成分的8个不同品种的整个大麻种子和8个样品的商业去皮大麻种子。我们还评估了酚类化合物和抗氧化剂，细胞毒性和抗微生物特性的水甲醇种子提取物。完整的大麻籽比去皮的大麻籽含有更多的纤维，后者含有更多的脂肪和蛋白质。蔗糖和棉子糖是最丰富的可溶性糖，柠檬酸和草酸是最丰富的有机酸。在火麻仁的水甲醇提取物中，我们检测到酚酸阿魏酸-己糖苷和胡萝卜酸。整个大麻籽提取物表现出更好的抗氧化活性比去皮大麻籽提取物，特别是在TBARS测定。还观察到对NCI-H460细胞的细胞毒性活性。去皮大麻籽提取物显示出抗菌活性，特别是对蜡状芽孢杆菌，单核细胞增生李斯特菌，粪肠球菌，和抗真菌活性在较小程度上。
This study aimed to determine a complete chemical composition of eight different varieties of whole hemp seeds and eight samples of commercial dehulled hemp seeds. We also evaluated the phenolic profiles and antioxidant, cytotoxic, and antimicrobial properties of hydromethanolic seed extracts. Whole hemp seeds contain much more fibre than dehulled hemp seeds, which contain more fat and protein. Sucrose and raffinose were the most abundant soluble sugars, and citric and oxalic acids were the most abundant organic acids. In the hydromethanolic hemp seed extracts, we detected the phenolic acids ferulic acid-hexoside and syringic acid. Whole hemp seed extracts exhibited better antioxidant activity than dehulled hemp seed extracts, especially in the TBARS assay. Cytotoxic activity against NCI-H460 cells was also observed. The dehulled hemp seed extracts displayed antibacterial activity, especially against Bacillus cereus, Listeria monocytogenes, and Enterococcus faecalis, and antifungal activity to a lesser extent.