Defective macrophage function in a patient with common variable immunodeficiency.
Defective macrophage function in a patient with common variable immunodeficiency.
复制标题
常见变异型免疫缺陷患者的巨噬细胞功能缺陷。
DOI:
10.1056/nejm198209233071307
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发表时间:
1982
期刊:
影响因子:
--
通讯作者:
C. Zielinski
中科院分区:
文献类型:
--
作者:
M. Eibl;J. Mannhalter;G. Zlabinger;W. Mayr;G. Tilz;R. Ahmad;C. Zielinski
COMMON variable immunodeficiency is characterized by different immunologic abnormalities responsible for agammaglobulinemia.1 In this disease, impaired B-cell differentiation has been observed at different levels,2 and defects of B-cell function in connection with abnormalities of regulatory T cells have been reported.3 4 5 6 Even though macrophages are known to play an essential part in the initiation and regulation of the immune response,7 a defect in macrophage function has not been identified in connection with common variable immunodeficiency. In this study, we report on a patient who, like most of our patients with common variable immunodeficiency, had a depressed T-cell proliferative response to Escherichia . . .
DOI:
10.1056/nejm198104023041403
发表时间:
1981
期刊:
The New England journal of medicine
影响因子:
--
作者:
Reinherz,EL;Geha,R;Wohl,ME;Morimoto,C;Rosen,FS;Schlossman,SF
通讯作者:
Schlossman,SF
DOI:
10.1073/pnas.78.8.5113
发表时间:
1981
影响因子:
11.1
作者:
Letvin,NL;Benacerraf,B;Germain,RN
通讯作者:
Germain,RN
DOI:
--
发表时间:
1981
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Todd3rd,RF;Nadler,LM;Schlossman,SF
通讯作者:
Schlossman,SF