Nodal recurrences following radical radiation therapy in Hodgkin's disease
Nodal recurrences following radical radiation therapy in Hodgkin's disease
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霍奇金病根治性放射治疗后淋巴结复发
DOI：
10.2214/ajr.120.3.536
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发表时间：
1974
期刊：
影响因子：
--
通讯作者：
R. Antemann
中科院分区：
文献类型：
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作者：
P. Rubin;H. Keys;E. Mayer;R. Antemann
用扩大野技术（套或倒Y）根治性照射后淋巴结疾病的复发很少能通过进一步的积极照射来控制。大多数淋巴结复发，不管它们是如何局限的，最终进展到淋巴结部位。由于射野重叠和重要正常结构重新照射的风险，通过照射管理淋巴结复发通常会出现特殊问题，本报告回顾性分析了123例临床I期和II期霍奇金病患者，这些患者接受了扩大野照射或第一次复发后5年生存率为：局部淋巴结复发者50%，经皮淋巴结转移者27%，经皮淋巴结转移者27%，经皮淋巴结转移者27%。而播散性疾病的复发率为0%。经皮扩散是mantle治疗后最常见的复发模式，
The re-appearance of nodal disease following radical irradiation with extended field technique (mantle or inverted Y) can rarely be controlled by further aggressive irradiation. The majority of nodal recurrences, regardless of how localized they are, eventually progress to extranodal sites. Managing nodal recurrences with irradiation often presents special problems due to overlap of fields and to risk of re-irradiation of vital normal structures, especially the spinal cord.This report is a retrospective review of 123 patients with clinical Stages I and II Hodgkin’s disease who have been treated with either extended field irradiation (mantle technique) or total nodal irradiation.The 5 year survival rates after the first relapse are: 50 per cent for patients with local nodal recurrence; 27 per cent for patients with transdiaphragmatic nodal extension; and 0 per cent for those with disseminated disease.The transdiaphragmatic extension, which is the most common recurrence pattern after treatment with mantle i...