AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides
AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides
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DOI：
10.26434/chemrxiv.11822289.v1
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发表时间：
2020-02
影响因子：
15
通讯作者：
Amanda M. Acevedo-Jake;Andrew T. Ball;M. Galli;M. Kukwikila;M. Denis;D. Singleton;A. Tavassoli;
中科院分区：
文献类型：
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作者：
Amanda M. Acevedo-Jake;Andrew T. Ball;M. Galli;M. Kukwikila;M. Denis;D. Singleton;A. Tavassoli;
我们提出了一种简单的策略来合成主链寡核苷酸轮烷，并精确控制大环的位置。分析了新型的基于DNA的轮烷，以评估机械键对其性质的影响。
We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.