Novel nucleophilic trifluoromethylation of vicinal diol cyclic sulfates
Novel nucleophilic trifluoromethylation of vicinal diol cyclic sulfates
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DOI：
10.1021/ol0270374
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发表时间：
2002-12-26
期刊：
影响因子：
5.2
通讯作者：
Dolbier, WR
中科院分区：
文献类型：
--
作者：
Takechi, N;Ait-Mohand, S;Dolbier, WR
[图形]提出了一种利用四（二甲氨基）乙烯（TDAE）还原碘化三氟甲基衍生的试剂对邻二醇环硫酸盐进行高区域选择性和立体特异性亲核三氟甲基化的新方法。
[GRAPHICS]A novel method for highly regioselective and stereospecific nucleophilic trifluoromethylation of vicinal diol cyclic sulfates, using the reagent derived from reduction of trifluoromethyl iodide by tetrakis(dimethylamino)ethylene (TDAE), is presented.