Effect of 1,25(OH)2D3 on the TSH Secretion from Rat Pituitary Cells
Effect of 1,25(OH)2D3 on the TSH Secretion from Rat Pituitary Cells
复制标题
1,25(OH)2D3 对大鼠垂体细胞 TSH 分泌的影响
DOI：
10.1055/s-2007-1012229
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
C. Lamberg
中科院分区：
文献类型：
--
作者：
K. Törnquist;C. Lamberg
1,25(OH)2D3 slightly increases basal TSH in the incubation media after a 24 h incubation with increasing amounts of the hormone. The TRH induced TSH response increased significantly in the presence of 10(-8)M 1,25(OH)2D3 (P less than 0.05). The intracellular concentration of TSH after the TRH test showed a slight decreasing tendency after a 24 h incubation with increasing amounts of 1,25(OH)2D3. The presence of verapamil (10(-8) M) and propranolol (10(-8) M) blunted the enhancing effect of 1,25(OH)2D3. The results indicate an effect of 1,25(OH)2D3 on the secretion of TSH.
