A full-factorial randomized controlled trial of adjunct couples HIV testing and counseling components addressing drug use and communication skills among sexual minority male couples.
A full-factorial randomized controlled trial of adjunct couples HIV testing and counseling components addressing drug use and communication skills among sexual minority male couples.
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DOI：
10.1186/s12889-021-12208-3
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发表时间：
2021-11-24
影响因子：
4.5
通讯作者：
Stephenson R
中科院分区：
文献类型：
--
作者：
Starks TJ;D Kyre K;B Cowles C;Castiblanco J;Washington C;N Parker J;M Kahle E;Stephenson R
在过去十年中，人们越来越关注为男性夫妇制定艾滋病毒预防干预措施，流行病学数据表明，主要或主要的伴侣关系-而不是因果关系-是这一人群中大量艾滋病毒感染的原因。夫妇艾滋病毒检测和咨询（CHTC）已成为美国的一项标准护理。该方案描述了一项旨在评估CHTC两个辅助成分-沟通培训（CT）视频和物质使用模块（SUM）-减少药物使用和性传播HIV风险行为的有效性的研究。符合条件的夫妇必须包括一名年龄在17-29岁、艾滋病毒阴性并报告最近吸毒的参与者。双方必须年满17岁，确认为cismale（出生时指定为男性，目前确认为男性），并用英语交流。在全因子设计中，夫妇在基线后被随机分配到四种条件之一（CHTC照常，CHTC + CT视频; CHTC + SUM和CHTC + CT视频+ SUM）。在基线后3、6、9和12个月完成随访评估。本试验结果将进一步促进CHTC的应用。如果发现有效，辅助组成部分将包括一个简短和可扩展的药物使用干预，可以很容易地纳入现有的艾滋病毒检测环境。 ClinicalTrials.gov方案注册; NCT 05000866; 2021年8月3日完成; https://register.clinicaltrials.gov/方案版本1.0; 2021年9月1日。
The past decade has seen increasing attention directed to the development of HIV prevention interventions for male couples, driven by epidemiological data indicating that main or primary – rather than causal – partnerships account for a substantial number of HIV infections in this population. Couples HIV testing and counseling (CHTC) has emerged as a standard of care in the US. This protocol describes a study that aims to evaluate the efficacy of two adjunct components to CHTC – communication training (CT) videos and a substance use module (SUM) – to reduce drug use and sexual HIV transmission risk behavior. Eligible couples must include one participant who is aged 17-29, HIV-negative, and reports recent drug use. Both partners must be aged 17 or older, identify as cismale (assigned male sex at birth and currently identify as male gender), and communicate in English. Couples are randomized post-baseline to one of four conditions (CHTC as usual, CHTC plus CT video; CHTC + SUM and CHTC + CT video + SUM) in a full-factorial design. Follow up assessments are completed at 3-, 6-, 9- and 12-months post baseline. Results of this trial will enhance the application of CHTC. If found effective, adjunct components would comprise a brief and scalable drug use intervention that could be readily integrated into existing HIV testing settings. ClinicalTrials.gov Protocol Registration; NCT05000866; completed August 3, 2021; https://register.clinicaltrials.gov/ Protocol version 1.0; September 1, 2021.
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影响因子：
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