NATIONAL GENERAL-PRACTICE STUDY OF EPILEPSY - RECURRENCE AFTER A 1ST SEIZURE
NATIONAL GENERAL-PRACTICE STUDY OF EPILEPSY - RECURRENCE AFTER A 1ST SEIZURE
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DOI：
10.1016/0140-6736(90)92960-p
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发表时间：
1990-11-24
期刊：
影响因子：
168.9
通讯作者：
SHORVON, SD
中科院分区：
文献类型：
--
作者：
HART, YM;SANDER, JWAS;SHORVON, SD
In the National General Practice Study of Epilepsy 564 patients classified as having definite seizures have been followed up for 2-4 years. 67% (95% confidence interval 63-71%) had a recurrence within 12 months at the first seizure, and 78% (74-81%) had a recurrence within 36 months. Seizures associated with a neurological deficit presumed present at birth had a high rate of recurrence (100% by 12 months), whereas seizures that occurred within 3 months of an acute insult to the brain, such as head injury or stroke, or in the context of an acute precipitant such as alcohol, carried a much lower risk of recurrence (40% [29-51%] by 12 months). Other factors affecting the risk of recurrence were age.sbd.the highest risk being for patients under the age of 16 (83% [77-89%] by 36 months) or over the age of 59 (83% [76-90%] by 36 months)-and type of first seizure.sbd.the risk of recurrence being much higher for patients with simple partial or complex partial seizures (94% [90-99%] by 36 months) than for those with generalised tonic clonic seizures (72% [67-77%] by 36 months).
