Electrochemical Decarboxylative Alkoxy-alkoxycarbonylation of Alkenes.
Electrochemical Decarboxylative Alkoxy-alkoxycarbonylation of Alkenes.
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DOI：
10.1021/acs.orglett.3c03816
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发表时间：
2023-12
期刊：
影响因子：
5.2
通讯作者：
Meiqun Lu;Kailun Chen;Tao Wu;Huanhuan Cai
中科院分区：
文献类型：
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作者：
Meiqun Lu;Kailun Chen;Tao Wu;Huanhuan Cai
研究了具有良好官能团相容性的乙草酸一钾盐的电化学阳极氧化法，用于各种烯烃与醇的烷氧基-烷氧基羰基化脱羧反应。该反应涉及阳极氧化以形成酰基，然后加成到烯烃上以产生新的烷基，该烷基被阳极氧化成碳阳离子并被醇捕获以提供β-烷氧基链烷酸酯。添加催化量的碘化铵提高了反应效率。
A method is presented for decarboxylative alkoxy-alkoxycarbonylation of various alkenes with alcohols by electrochemical anodic oxidation of monopotassium ethyloxalate salts with good functional group compatibility. The reaction involves anodic oxidation to form an acyl radical, followed by addition to an olefin to yield a new alkyl radical, which is anodically oxidized to a carbon cation and captured by alcohols to afford β-alkoxyalkanoates. Adding catalytic amounts of ammonium iodide enhanced the efficiency of the reactions.