Association of sleep characteristics with cardiovascular and metabolic risk factors in a population sample: the Chicago Area Sleep Study.

Association of sleep characteristics with cardiovascular and metabolic risk factors in a population sample: the Chicago Area Sleep Study.
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DOI:
10.1016/j.sleh.2017.01.003
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发表时间:
2017-04
期刊:
影响因子:
4.1
通讯作者:
Carnethon MR
Carnethon MR
中科院分区:
医学2区
文献类型:
--
作者:
Montag SE;Knutson KL;Zee PC;Goldberger JJ;Ng J;Kim KA;Carnethon MR

文献摘要

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To investigate the association of sleep characteristics with prevalent hypertension, diabetes, and obesity in a multiethnic cohort. This study used a population based cross-sectional study design. Participants were recruited between 2009 and 2011 from Chicago, Illinois and the surrounding suburbs. Participants were 492 adults ages 35–64 years old who self-reported as white, black, Hispanic or Asian and who had a low likelihood of sleep apnea based on the apnea screening questionnaires and 1 night of apnea screening using an in-home device (apnea hypopnea index [AHI] <15 or oxygen desaturation index [ODI]<10). Participants wore a wrist actigraphy monitor (Actiwatch™) for 7 days. During a clinical examination, participants completed questionnaires about sleep, other health behaviors and medical history and had their blood pressure, anthropometric measures and fasting blood glucose measured; metabolic risk factors were determined based on standard clinical guidelines. The prevalence of hypertension, obesity and diabetes was 17.1%, 5.5% and 35.4%, respectively. Sleep duration was not associated with any cardiovascular risk factor. There was a significantly increased odds for hypertension (OR: 1.05 95%CI: 1.01, 1.08) and obesity (OR: 1.03 95%CI: 1.00, 1.05) associated with higher sleep fragmentation (per 1%). There was also a significantly increased odds for hypertension associated with poorer self-reported sleep quality (OR 1.14 95%CI: 1.05, 1.24 per 1 unit higher Pittsburgh Sleep Quality Index global score). Objective and self-reported sleep quality may be more important than duration in relation to prevalent hypertension.