First experience with monochromatic coronary computed tomography angiography from a 64-slice CT scanner with Gemstone Spectral Imaging (GSI)
First experience with monochromatic coronary computed tomography angiography from a 64-slice CT scanner with Gemstone Spectral Imaging (GSI)
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DOI：
10.1016/j.jcct.2013.01.004
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发表时间：
2013-01-01
影响因子：
5.4
通讯作者：
Kaufmann, Philipp A.
中科院分区：
文献类型：
--
作者：
Fuchs, Tobias A.;Stehli, Julia;Kaufmann, Philipp A.
背景：将双能量CT和最新的宝石探测器用于光谱成像的新技术可以用来合成模拟图像的单色图像，就好像使用不同的单色X射线源一样。目的：本研究的目的是评价单色图像能量和自适应统计迭代重建(ASIR)的最佳组合用于冠状动脉CT血管成像(CTA)图像的单色重建。方法：连续20例患者在具有GSI功能的层CT扫描仪(Discovery CT750高清晰度，GE Healthcare)上进行冠状动脉CTA。在7组单色图像(60、65、70、75、80、90和110 Key；每组图像具有递增的ASIR贡献，即0%、20%、40%、60%和80%；每个患者35个重建)中，评估信噪比(主动脉根部)和对比噪声比(左主干)。结果：与常规多色图像相比，60Key和80%ASIR重建图像的对比度噪声比(144%；P<；0.001)和信噪比(173%；P<；0.001)均有最大改善。采用40%~60%的ASIR混合后，图像质量在65-75帧达到平台期，与常规成像相比，图像质量分数最大提高50%(P<；0.001)。结论：在低辐射技术(平均辐射剂量，1.8+/-0.7mSv)的冠状动脉CTA中，单色重建(65-75帧)和ASIR(40%-60%)的GSI具有显著的降噪和图像质量改善。(C)2013年心血管计算机断层扫描学会。版权所有。
Background: New technology combining dual-energy CT with the latest gemstone detectors for spectral imaging (GSI) can be used to synthesize monochromatic images that mimic images as if different monochromatic x-ray sources were used.Objective: The aim of the study was to evaluate the optimal combination of monochromatic image energy and adaptive statistical iterative reconstruction (ASiR) for monochromatic reconstruction of coronary CT angiography (CTA) images with the use of GSI.Methods: Twenty consecutive patients underwent coronary CTA on a GSI capable 64-slice CT scanner (Discovery CT 750 High Definition, GE Healthcare). In 7 sets of monochromatic images (60, 65, 70, 75, 80, 90, and 110 key; each with increasing contributions of ASiR, ie, 0%, 20%, 40%, 60%, and 80%; n = 35 reconstructions per patient), signal-to-noise (aortic root) and contrast-to-noise (left main artery) ratios were assessed. Signal-to-noise ratio, contrast-to-noise ratio, and image quality (graded on a 5-point Likert scale) were assessed in all above monochromatic reconstructions and compared with the respective standard (conventional polychromatic) image.Results: Compared with conventional polychromatic images, reconstructions with 60 key and 80% ASiR showed the highest improvement in contrast-to-noise (144%; P < 0.001) and signal-to-noise ratio (173%; P < 0.001). Image quality reached a plateau at 65-75 key with 40%-60% ASiR blending, yielding a maximal image quality score improvement of 50% compared with conventional imaging (P < 0.001).Conclusion: In coronary CTA with low radiation technique (mean radiation dose, 1.8 +/- 0.7 mSv), GSI with monochromatic reconstructions (65-75 key) and ASiR (40%-60%) offers significant noise reduction and image quality improvement. (C) 2013 Society of Cardiovascular Computed Tomography. All rights reserved.