From dogs to frogs: how pets, laboratory animals, and wildlife aided in elucidating harmful effects arising from a hazardous dumpsite.
From dogs to frogs: how pets, laboratory animals, and wildlife aided in elucidating harmful effects arising from a hazardous dumpsite.
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从狗到青蛙：宠物、实验动物和野生动物如何帮助阐明危险垃圾场产生的有害影响。
DOI：
10.1093/ilar.46.4.364
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发表时间：
2005
期刊：
影响因子：
2.5
通讯作者：
Arquette,MaryFadden
中科院分区：
文献类型：
--
作者：
Quimby,FredW;Casey,AnnC;Arquette,MaryFadden
医学文献中有许多偶然观察导致重要发现的案例。在这篇文章中描述的例子中，在Akwesasne的莫霍克民族社区进行的实验室和实地观察导致了一个重要而意想不到的发现，即该地区曾经大量繁殖的青蛙不再被观察到。实验室测试比较了来自阿克韦森的河流沉积物和来自纽约伊萨卡的原始沉积物，表明对发育中的青蛙有多种不利的健康影响。在实验室中观察到的一些行为变化与阿克韦森内居民在两栖动物开始衰退之前所描述的相似。蛙体中多氯联苯的变化幅度与阿克wesasne沉积物中多氯联苯的负荷相似。讨论了这些发现对危险废物场地识别和全球两栖动物衰退的影响。
The medical literature contains many examples of cases in which serendipitous observations have led to important findings. In the example described in this article, laboratory and field observations conducted at the Mohawk Nation Community of Akwesasne led to the important and unexpected finding that frogs once plentiful in the area were no longer observed. Laboratory tests comparing river sediments from Akwesasne to pristine sediment from Ithaca, New York, indicated multiple adverse health effects on developing frogs. Some of the behavioral changes observed in the laboratory were similar to those described by residents of Akwesasne before the onset of amphibian decline. The magnitude of changes paralleled frog body burden of polychlorinated biphenyls acquired from the Akwesasne sediment. The impact of these findings on the identification of a hazardous waste site and global amphibian decline are discussed.