Facile synthesis of Fe@Fe2O3 nanochains exhibiting high heating efficiency in magnetic hyperthermia
Facile synthesis of Fe@Fe2O3 nanochains exhibiting high heating efficiency in magnetic hyperthermia
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DOI：
10.1016/j.jallcom.2016.04.141
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发表时间：
2016-10
影响因子：
6.2
通讯作者：
Liqun Wang;Xuegang Lu;Jieqiong Wang;Sen Yang;Xiaoping Song
中科院分区：
文献类型：
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作者：
Liqun Wang;Xuegang Lu;Jieqiong Wang;Sen Yang;Xiaoping Song
铁磁纳米粒子（NPs）具有高加热效率，作为加热元件在磁热疗和热消融治疗中具有巨大的潜力。在这项工作中，通过在水溶液中轻松化学还原 Fe2+ 离子制备了核@壳结构的 Fe@Fe2O3 纳米链。通过X射线粉末衍射（XRD）、扫描电子显微镜（SEM）、透射电子显微镜（TEM）、元素图、拉曼分析和磁化测量对所得纳米链进行了表征。研究发现，Fe纳米链是由Fe纳米球一一连接而成，并被非晶态Fe2O3层包裹。这些链的直径约为 50-100 纳米，长度为几微米。磁测量表明，所制备的纳米结构具有典型的铁磁性，特征阻挡温度高于400 K。在25 °C、40 °C和80 °C制备的样品的饱和磁化强度分别为118.6、81.9、22.8 emu/g，矫顽力分别为136、259和411 Oe。有趣的是，这些纳米链分散在生理 pH 值的水中，具有比超顺磁性铁氧体纳米颗粒更高的加热效率。 Fe@Fe2O3纳米链加热性能的增强可能归因于磁滞损耗机制的激活。这项研究表明，由此产生的 Fe@Fe2O3 纳米链是磁热疗和热消融疗法中很有前途的材料。
Ferromagnetic nanoparticles (NPs), with high heating efficiency, have great potential as heating elements for use in magnetic hyperthermia and thermoablation therapies. In this work, core@shell structured Fe@Fe2O3nanochains were prepared by facile chemical reduction of Fe2+ions in aqueous solution. The resulting nanochains were characterized by X-ray powder diffraction(XRD), scanning electron microscopy(SEM), transmission electron microscopy(TEM), elemental mapping, Raman analysis, and magnetization measurements. It was found that Fe nanochains form through connection of Fe nanospheres one by one and are coated by amorphous Fe2O3layer. The chains are about 50–100 nm in diameter and several micrometers in length. Magnetic measurements revealed that as-prepared nanoconstructs possess typical ferromagnetism with a characteristic blocking temperature above 400 K. The saturation magnetization of the samples prepared at 25 °C, 40 °C and 80 °C are 118.6, 81.9, 22.8 emu/g and the coercivity are 136, 259 and 411Oe, respectively. It was interesting to find that these nanochains, dispersed in water at physiological pH, present higher heating efficiency than that of superparamagnetic ferrite NPs. The enhanced heating performance of Fe@Fe2O3nanochains may be attributed to the activation of a magnetic hysteresis loss mechanism. This study indicates that the resulting Fe@Fe2O3nanochains are promising materials in magnetic hyperthermia and thermoablation therapies.