Logic gate aggregation of poly(N-isopropylacrylamide) nanogels with catechol substituents that respond to body heat
Logic gate aggregation of poly(N-isopropylacrylamide) nanogels with catechol substituents that respond to body heat
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DOI：
10.1038/s41428-018-0042-x
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发表时间：
2018-04
期刊：
影响因子：
2.8
通讯作者：
Shingo Tamesue;S. Abe;T. Endo;T. Yamauchi
中科院分区：
文献类型：
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作者：
Shingo Tamesue;S. Abe;T. Endo;T. Yamauchi
智能水凝胶材料是一个热门的研究课题，因为它们有可能被用作智能药物载体和软致动器。显示对逻辑门型刺激的响应性的水凝胶材料是特别感兴趣的，因为它们的响应性可以比常见的刺激响应性材料更精确地调节。本研究采用沉淀聚合法制备了网络结构中含有邻苯二酚取代基的聚（N-异丙基丙烯酰胺）纳米凝胶。所制备的纳米凝胶表现出与型逻辑门的热聚集行为。研究了这种逻辑门型智能纳米凝胶聚集系统在智能阀系统中的可能用途。
Smart hydrogel materials are a popular topic of investigation because they have the potential to be used as smart drug carriers and soft actuators. Hydrogel materials showing responsiveness to logic gate-type stimuli are of special interest because their responsiveness can be regulated more accurately than that of common stimuli-responsive materials. In this study, poly(N-isopropylacrylamide) nanogels containing catechol substituents in their polymer network structure were prepared via precipitation polymerization. The prepared nanogels showed AND-type logic gate thermal aggregation behavior. The possible use of this logic gate-type smart nanogel aggregating system was investigated in a smart valve system.