SUBVALVULAR AND APICAL LEFT VENTRICULAR ANEURYSMS IN BANTU AS A SOURCE OF SYSTEMIC EMBOLI
SUBVALVULAR AND APICAL LEFT VENTRICULAR ANEURYSMS IN BANTU AS A SOURCE OF SYSTEMIC EMBOLI
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DOI：
10.1161/01.cir.35.6.1156
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发表时间：
1967-01-01
期刊：
影响因子：
37.8
通讯作者：
BARLOW, JB
中科院分区：
文献类型：
--
作者：
CHESLER, E;TUCKER, RBK;BARLOW, JB
在2例Bantu患者中描述了起源于心尖部和瓣膜下室壁瘤的系统性栓子。这些动脉瘤的罕见栓塞率可能与此类动脉瘤通常有较小的开口处有关。回顾相关文献，并讨论这些动脉瘤、先天性心外膜囊肿和纤维性憩室之间的相似性。据推测，这些疾病都有一个共同的病因，即以持续性原始内皮内衬通道的形式表现的先天性左室壁薄弱。在室壁最薄的两个部位，即心尖区和瓣下区，左室内的高压将这些通道转化为纤维性壁瘤，其开口由心内膜覆盖。
Systemic emboli originating from apical and subvalvular left ventricular aneurysms are described in 2 Bantu patients. The infrequency of embolism from these aneurysms is probably related to the fact that such aneurysms usually have small ostia. The pertinent literature is reviewed and the similarity between these aneurysms, congenital epicardial cysts, and fibrous diverticula is discussed. It is postulated that these conditions share a common etiology, namely, a congenital weakness in the left ventricular wall in the form of a persistent primitive endothelial-lined channel. The high pressure in the left ventricle converts these channels into fibrous aneurysms with ostia lined by endocardium at the 2 sites where the ventricular wall is thinnest, namely, the apical and subvalvular areas.