Epidemiology of psoriatic disease and current treatment patterns from 2003 to 2013: A nationwide, population-based observational study in Taiwan
Epidemiology of psoriatic disease and current treatment patterns from 2003 to 2013: A nationwide, population-based observational study in Taiwan
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DOI：
10.1016/j.jdermsci.2016.08.535
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发表时间：
2016-12-01
影响因子：
4.6
通讯作者：
Tsai, Tsen-Fang
中科院分区：
文献类型：
--
作者：
Wang, Ting-Shun;Hsieh, Chi-Feng;Tsai, Tsen-Fang
背景资料：最近的全球数据显示，银屑病和银屑病关节炎在西方国家的患病率不断增加，目的：本研究分析了银屑病和银屑病关节炎在台湾的患病率的趋势，并检查生物处方模式的不同specials.Methods：数据来自国家支付人国民健康保险研究数据库在台湾。本研究方案经医学研究伦理基金会成立的联合机构审查委员会批准（编号13-S-001）。结果：2003年至2013年间，银屑病和银屑病关节炎的患病率上升了41%（从15.54/万上升到21.90/万）和191%（从0.45/万上升到1.31/万），而银屑病患者中银屑病关节炎的患病率从6.3%上升到12.7%。皮肤科医生是银屑病和银屑病关节炎患者的主要照顾者;然而，数据显示，银屑病患者的皮肤科医生比例呈下降趋势，从2003年至2008年的24.7%降至2008年至2013年的10.74%，同期银屑病关节炎患者的皮肤科医生相应从62.30%下降到44.65%。2013年，在51,191例银屑病患者中，只有596例（1.16%）接受了生物制剂治疗（73.3%由皮肤科医生治疗，25.8%由风湿科医生治疗），而在7470例银屑病关节炎患者中，有1120例（14.99%）接受了生物制剂治疗（72.8%由风湿科医生治疗，223%由皮肤科医生治疗）。在皮肤科医师及风湿科医师所诊断的单纯银屑病患者中，生物制剂使用比例分别为1.12%及7.75%，而在银屑病关节炎患者中，生物制剂使用比例分别为8.01%及26.70%。银屑病关节炎患者使用生物制剂的情况与美国和欧洲先前研究报告的情况相当;然而，台湾银屑病患者使用生物制剂的情况仍然很低。(C)2016年日本皮肤病研究学会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Background: Recent global data show an increasing prevalence of psoriasis and psoriatic arthritis in western countries.Objective: The current study analyzed the trend of prevalence rates of psoriasis and psoriatic arthritis in Taiwan and examined biologic prescription patterns by different specialties.Methods: Data were accessed from the national payer National Health Insurance Research Database in Taiwan. This study protocol was approved by Joint Institutional Review Board established by Medical Research Ethics Foundation (No 13-S-001).Results: Between 2003 and 2013, the prevalence of psoriasis and psoriatic arthritis increased by 41% (from 15.54 to 21.90 per 10,000 population) and 191% (from 0.45 to 1.31 per 10,000 population), respectively, while the prevalence of psoriatic arthritis among patients with psoriatic disease increased from 6.3% to 12.7%. Dermatologists are the main caregivers for patients with psoriasis and psoriatic arthritis; however, data suggest a decreasing trend in the proportion of dermatologists for psoriasis patients from 24.7% between 2003 and 2008 to 10.74% between 2008 and 2013, with a corresponding decrease in dermatologists for psoriatic arthritis patients from 62.30% to 44.65% during the same periods, respectively. In 2013, of the 51,191 patients with psoriasis, only 596 (1.16%) received biologics (73.3% by dermatologists and 25.8% by rheumatologists), while 1120 of the 7470 (14.99%) psoriatic arthritis patients received biologics (72.8% by rheumatologists and 223% by dermatologists). The proportion Of biologics use was 1.12% and 7.75% among all patients with only psoriasis and 8.01% and 26.70% among all patients with psoriatic arthritis seen by dermatologists and rheumatologists, respectively.Conclusion: The prevalence of psoriasis and psoriatic arthritis is increasing in Taiwan. The use of biologics in patients with psoriatic arthritis was comparable to that reported in previous studies in the United States and Europe; however, the use of biologics remained low in patients with psoriasis in Taiwan. (C) 2016 Japanese Scciety for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.