Anemia and iron deficiency: effects on pregnancy outcome
Anemia and iron deficiency: effects on pregnancy outcome
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DOI：
10.1093/ajcn/71.5.1280s
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发表时间：
2000-05-01
影响因子：
7.1
通讯作者：
Allen, LH
中科院分区：
文献类型：
--
作者：
Allen, LH
本文综述了目前对母亲贫血和铁缺乏对妊娠结局影响的认识。关于母亲补充铁对怀孕期间和产后母亲及其子女的健康和铁状况的益处，仍有大量信息有待了解。目前的知识表明，妊娠期缺铁性贫血是早产和随后的低出生体重的危险因素，并可能为较差的新生儿健康。数据不足以确定产妇贫血在多大程度上可能导致产妇死亡。即使对于怀孕时有合理铁储备的妇女，铁补充剂也能改善怀孕期间和产后相当长一段时间的铁状况，从而在随后的怀孕中提供一些保护，防止铁缺乏。越来越多的证据表明，母亲在怀孕期间缺铁会减少胎儿的铁储备，可能会一直持续到生命的第一年。这值得进一步探讨，因为婴儿的倾向，发展缺铁性贫血，因为这种情况对婴儿发育的不良后果的文件。大量证据支持妊娠期间常规补铁的可行性。
This article reviews current knowledge of the effects of maternal anemia and iron deficiency on pregnancy outcome. A considerable amount of information remains to be learned about the benefits of maternal iron supplementation on the health and iron status of the mother and her child during pregnancy and postpartum. Current knowledge indicates that iron deficiency anemia in pregnancy is a risk factor for preterm delivery and subsequent low birth weight, and possibly for inferior neonatal health. Data are inadequate to determine the extent to which maternal anemia might contribute to maternal mortality. Even for women who enter pregnancy with reasonable iron stores, iron supplements improve iron status during pregnancy and for a considerable length of time postpartum, thus providing some protection against iron deficiency in the subsequent pregnancy. Mounting evidence indicates that maternal iron deficiency in pregnancy reduces fetal iron stores, perhaps well into the first year of life. This deserves further exploration because of the tendency of infants to develop iron deficiency anemia and because of the documented adverse consequences of this condition on infant development. The weight of evidence supports the advisability of routine iron supplementation during pregnancy.