Mechanisms for oscillation and frequency control in reciprocally inhibitory model neural networks.
Mechanisms for oscillation and frequency control in reciprocally inhibitory model neural networks.
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DOI：
10.1007/bf00962719
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发表时间：
1994-06-01
影响因子：
1.2
通讯作者：
Marder, E
中科院分区：
文献类型：
--
作者：
Skinner, F K;Kopell, N;Marder, E
我们描述了四种不同的机制，导致振荡在两个相互抑制细胞的网络。在两种情况下（内在释放和内在逃逸），网络振荡的频率对突触电位的阈值电压不敏感。在另外两种情况下（突触释放和突触逃逸），网络频率在很大程度上取决于突触连接的阈值电压。随着描述突触激活的功能变得不那么明显，以及模型神经元从松弛状态中移除，不同机制之间的区别变得模糊了。这些机制提供了对电机系统中控制网络频率的参数的深入了解，这些参数依赖于相互抑制。
We describe four different mechanisms that lead to oscillations in a network of two reciprocally inhibitory cells. In two cases (intrinsic release and intrinsic escape) the frequency of the network oscillation is insensitive to the threshold voltage of the synaptic potentials. In the other two cases (synaptic release and synaptic escape) the network frequency is strongly determined by the threshold voltage of the synaptic connections. The distinction between the different mechanisms blurs as the function describing synaptic activation becomes less steep and as the model neurons are removed from the relaxation regime. These mechanisms provide insight into the parameters that control network frequency in motor systems that depend on reciprocal inhibition.