Measles in a highly vaccinated society: The 2007-08 outbreak in Israel

Measles in a highly vaccinated society: The 2007-08 outbreak in Israel
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DOI:
10.1016/j.jinf.2009.07.005
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发表时间:
2009-10-01
影响因子:
28.2
通讯作者:
Israeli, Avi
Israeli, Avi
中科院分区:
医学1区
文献类型:
--
作者:
Anis, Emilia;Grotto, Itamar;Israeli, Avi

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背景资料:尽管通过国家免疫计划成功控制了麻疹,但以色列最近经历了自1994年以来最大的麻疹疫情。方法:利用卫生区办事处向卫生部报告的数据,对2007-08年麻疹疫情进行流行病学分析。以色列报告了1 467例麻疹病例,主要发生在耶路撒冷卫生区的极端正统派犹太社区,其他地区也有少量病例。最高的年龄别发病率(每100 000人122.5人)发生在婴儿中。5岁以下儿童占麻疹发病总数的38.6%,10岁以下儿童占53.4%。186例患者(12.7%)住院;无死亡。只有4.6%的麻疹患者已完全接种疫苗,为他们的年龄。结论:为了尽量减少未来在以色列爆发的风险,成功营销的MMR疫苗接种不足的亚组是必不可少的。(C)2009年,英国传染病协会。由爱思唯尔有限公司出版。保留所有权利。
Background: Despite success in controlling measles through a national immunization program, Israel recently experienced its largest measles outbreak since 1994.Methods: Using data reported by health district offices to the Ministry of Health, an epidemiological analysis of the 2007-08 measles outbreak was performed.Results: 1467 measles cases were reported in Israel, primarily among ultra-orthodox Jewish communities in the Jerusalem Health District and to a lesser extent in other areas. The highest age-specific incidence rate (122.5 per 100,000) occurred among infants. 38.6% of all measles patients were under the age of five, and 53.4% were under the age of ten. 186 patients (12.7%) were hospitalized; there were no fatalities. Only 4.6% of measles patients had been fully vaccinated for their age.Conclusion: To minimize the risk of future outbreaks in Israel, successful marketing of the MMR vaccine to under-vaccinated sub-groups is essential. (C) 2009 The British Infection Society. Published by Elsevier Ltd. All rights reserved.