Incidence and psychological-behavioral characteristics of refractory functional dyspepsia: A large, multi-center, prospective investigation from China
Incidence and psychological-behavioral characteristics of refractory functional dyspepsia: A large, multi-center, prospective investigation from China
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DOI：
10.3748/wjg.v21.i6.1932
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发表时间：
2015-02-14
影响因子：
4.3
通讯作者：
Li, Wei-Dong
中科院分区：
文献类型：
--
作者：
Jiang, Shu-Man;Jia, Lin;Li, Wei-Dong
目的：目的：探讨我国难治性功能性消化不良（RFD）的发病率及心理行为特征。方法：以1341例门诊新诊断的功能性消化不良（FD）患者为研究对象，根据罗马标准进行诊断。2012年6月至9月，在广东省的四家医院和100名健康志愿者的标准。结果：1341例FD患者中有327例（24.4%）有RFD。与非难治性FD（NRFD）患者相比，RFD患者的病程更长，疾病形式更严重。RFD组抑郁、焦虑症状发生率高于NRFD组。RFD患者的不健康饮食行为、缺乏体力活动和睡眠障碍的患病率高于NRFD患者。与NRFD患者相比，RFD患者寻求医疗咨询的次数更多，治疗费用也更多。结论：RFD在临床上并不少见，因其病程长、症状重、伴有心理异常、生活质量差，应引起患者和医生的重视。
AIM: To explore the incidence and psychological and behavioral characteristics of refractory functional dyspepsia (RFD) in China.METHODS: The subjects of this study were 1341 new outpatients with functional dyspepsia (FD) who were diagnosed according to the Rome. criteria at four hospitals in Guangdong Province between June and September 2012, and 100 healthy volunteers. All subjects completed questionnaires and scales administered.RESULTS: Three-hundred and twenty-seven of the 1341 patients with FD had RFD (24.4%). Patients with RFD had a longer disease duration and a more severe form of the disease than patients with non-refractory FD (NRFD). The prevalence of depression and anxiety symptoms was higher in patients with RFD than in patients with NRFD. The prevalence of unhealthy eating behaviors, lack of physical activity, and sleeping disorders was higher in patients with RFD than in patients with NRFD. Patients with RFD sought medical advice on more occasions and spent more money on treatment than patients with NRFD. Finally, patients with RFD had poorer quality of life than patients with NRFD.CONCLUSION: RFD is not rare in clinical practice and should get attention by patients and doctors because of its long duration, severe symptoms, and associations with abnormal psychology and poor quality of life.