Performance of the National Early Warning Score in Hospitalized Patients With Kidney Failure on Maintenance Hemodialysis.
Performance of the National Early Warning Score in Hospitalized Patients With Kidney Failure on Maintenance Hemodialysis.
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DOI：
10.1016/j.xkme.2022.100506
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发表时间：
2022-08
期刊：
影响因子：
3.9
通讯作者：
Goldstein, Benjamin A.
中科院分区：
文献类型：
--
作者：
Cavalier, Joanna;Zhao, Congwen;Scialla, Julia;Bedoya, Armando;Goldstein, Benjamin A.
早期预警评分已成为住院患者的标准临床决策支持工具。它们旨在预测失代偿，通常定义为计划外转移到重症监护室或医疗楼层患者的死亡率。预警评分有几十种，其中最常用的是国家预警评分（NEWS），这是一个由7个生命体征组成的简单评分。1，2尽管研究表明NEWS和其他早期预警评分具有足够的预测性能，2，3这些评分在临床亚群中的实用性还不太确定。早期预警评分已在肾移植受者中进行了检查，4但其在接受维持性血液透析治疗的肾衰竭患者中的使用仅在大型研究中作为亚群分析进行了检查。5由于这些患者具有独特的血液动力学，并且在透析治疗期间经常捕获异常的生命体征，因此尚不清楚NEWS是否适用于该人群。我们试图评估NEWS在维持性血液透析住院患者中的性能。所有分析均在R 4.0中进行。3.这项工作由杜克大学机构审查委员会根据Pro00108813批准，鉴于研究的性质，该委员会放弃了知情同意的要求。
Early warning scores have become a standard clinical decision support tool for hospitalized patients. They are designed to predict decompensation, defined typically as unplanned transfer to the intensive care unit or mortality in patients on a medical floor. There are dozens of early warning scores, of which one of the most commonly used is the National Early Warning Score (NEWS), a simple score consisting of 7 vital signs. 1, 2Although studies have shown the NEWS and other early warning scores to have adequate predictive performance, 2, 3 the utility of these scores in clinical subpopulations is less well established. Early warning scores have been examined in kidney transplant recipients, 4 but their use in patients with kidney failure treated on maintenance hemodialysis has only been examined as subpopulation analyses in larger studies. 5 Because these patients have unique hemodynamics and often abnormal vitals captured during dialysis treatment, it is unknown whether the NEWS is useful in this population. We sought to evaluate the performance of the NEWS in hospitalized patients on maintenance hemodialysis. All analyses were performed in R 4.0. 3. This work was approved by the Duke University Institutional Review Board under Pro00108813, which waived the requirement for informed consent given the nature of the research.
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影响因子：
8.8
作者：
Bedoya AD;Clement ME;Phelan M;Steorts RC;O'Brien C;Goldstein BA
通讯作者：
Goldstein BA
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Turan, Mustafa