A novel device for measuring arterial stiffness using finger-toe pulse wave velocity: Validation study of the pOpmetre®
A novel device for measuring arterial stiffness using finger-toe pulse wave velocity: Validation study of the pOpmetre®
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DOI：
10.1016/j.acvd.2014.12.003
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发表时间：
2015-04-01
影响因子：
3
通讯作者：
Laurent, Stephane
中科院分区：
文献类型：
--
作者：
Alivon, Maureen;Thao Vo-Duc Phuong;Laurent, Stephane
背景资料。--手指-脚趾径路可能是一种方便地评估动脉僵硬的好方法。-评估pOpmetre(R)-一种测量指趾脉搏波速度(ft-PWV)的新设备的准确性。-pOpmetre有两个光电二极管传感器，分别位于手指和脚趾上。连续记录脉搏波20秒，计算足趾和手指脉搏波传播时间之差(ft-Tt)。旅行距离是使用对象高度来估计的。研究1比较了86例受试者(平均年龄53±20岁)的fT-PWV和参考方法(SPhygmoCor(R))获得的颈动脉-股动脉PWV(cf-PWV)，其中包括69例各种疾病患者和17例正常血压者。研究2比较了10名健康受试者在冷加压试验中ft-pwv和cf-pwv的变化。研究3评估了45名患者的可重复性。-ft-Pwv与cf-Pwv显著相关(R-2=0.43；P<；0.0001)。在通过时间方面有较好的相关性(R-2=0.61P<；0.0001)。中转时间的差异与年龄有关。冷加压试验引起cf-PWV和ft-PWV的平行变化，主动脉僵硬增加，在恢复期间是可逆的。批内重复性好，变异系数为4.52%。--pOpmetre(R)允许在常规临床实践中测量动脉硬度。FT-PWV的最大优点是简单、快速、可行、患者可接受，并与参考技术正确一致。需要进一步的研究来调整偏倚，并在更大的人群中验证pOpmetre。(C)2015年爱思唯尔·马森公司。版权所有。
Background. - The finger-toe pathway could be a good alternative for assessing arterial stiffness conveniently.Aim. - To evaluate the accuracy of the pOpmetre (R) - a new device that measures finger-toe pulse wave velocity (ft-PWV).Methods. - The pOpmetre has two photodiode sensors, positioned on the finger and the toe. Pulse waves are recorded continuously for 20 seconds, and the difference in pulse wave transit time between toe and finger (ft-TT) is calculated. The travelled distance is estimated using subject height. Study 1 compared ft-PWV with carotid-femoral PWV (cf-PWV) obtained by the reference method (SphygmoCor (R)) in 86 subjects (mean age 53 +/- 20 years), including 69 patients with various pathologies and 17 healthy normotensives. Study 2 compared changes in ft-PWV and cf-PWV during a cold pressor test in 10 healthy subjects. Study 3 assessed repeatability in 45 patients.Results. - ft-PWV correlated significantly with cf-PWV (R-2 = 0.43; P < 0.0001). A better correlation was found in terms of transit time (R-2 = 0.61; P < 0.0001). The discrepancy between transit times was related to age. The cold pressor test induced parallel changes in cf-PWV and ft-PWV, with increased aortic stiffness that was reversible during recovery. Intra-session repeatability was very good, with a coefficient of variation of 4.52%.Conclusion. - The pOpmetre (R) allows measurement of arterial stiffness in routine clinical practice. The greatest advantages of ft-PWV are simplicity, rapidity, feasibility, acceptability by patients and correct agreement with the reference technique. Further studies are needed to adjust for bias and to validate the pOpmetre in larger populations. (C) 2015 Elsevier Masson SAS. All rights reserved.