Short-Term Deposition of PM2.5 Particles on Contact Lens Surfaces: Effect on Oxygen Permeability and Refractive Index
Short-Term Deposition of PM2.5 Particles on Contact Lens Surfaces: Effect on Oxygen Permeability and Refractive Index
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PM2.5 颗粒在隐形眼镜表面的短期沉积：对透氧率和折射率的影响
DOI：
10.1080/02713683.2018.1476552
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发表时间：
2018-01-01
影响因子：
2
通讯作者：
Li, Juan
中科院分区：
文献类型：
--
作者：
Dong, Zhizhang;Ding, Xiaoyan;Li, Juan
目的：研究直径2.5m的细颗粒物(PM2.5)在隐形眼镜表面的沉积情况，并探讨其对隐形眼镜透氧性(OP)和屈光率(RI)的影响。RGP晶状体(n=12)和SCL(n=12)(实验组)在PM2.5溶液中孵育24小时后，PM2.5处理的RGP晶状体(n=6)和SCL(n=6)在磷酸盐缓冲液(PBS)中洗涤1h。所有晶状体用场发射扫描电子显微镜进行检查。结果：角膜接触镜和晶状体表面浸泡在PM2.5溶液中的PM2.5平均粒径分别为3.1921.637和2.158+/-1.187/100m(2)。在RGP透镜表面，我们观察到了大颗粒(直径2.5微米)和小颗粒(PM2.5)。PM2.5颗粒以弥散的方式沉积，主要沿SCL的蜂窝结构边缘，而在SCL表面的蜂窝孔中未发现PM2.5颗粒。在PBS中清洗去除了RGP镜片表面较大的PM颗粒，但留下了大量的PM2.5颗粒。相比之下，PBS清洗后，SCL表面几乎所有的PM颗粒都被去除。PM2.5沉积对RGP晶状体和SCL的OP值无明显影响。PM2.5沉积后，RGP晶状体和SCL组的RI值均升高。然而，这些增加没有统计学意义，提示PM2.5沉积本身不会引起隐形眼镜RI的波动。结论：PM2.5颗粒在隐形眼镜表面的沉积因镜片材料的不同而不同。PM2.5颗粒沉积在SCL上，但只有RGP表面的大颗粒能够通过PBS清洗而被去除，并且似乎不改变两种透镜类型的OP和RI。
Purposes: To identify the deposition of fine (2.5m diameter) particulate matter (PM) particles (PM2.5) on contact lens surfaces and to investigate the effects of such deposition on the oxygen permeability (OP) and refractive index (RI) of contact lenses.Methods: A total of 36 contact lenses, including rigid gas permeable (RGP) lens and soft contact lens (SCL), were investigated. RGP lens (n=12) and SCL (n=12) (experimental group) were incubated in a PM2.5 solution for 24h, after which PM2.5-treated RGP lens (n=6) and SCL (n=6) were further washed for 1h in phosphate-buffered saline (PBS). All lenses were examined by field emission scanning electron microscopy. OP and RI of all lenses were measured.Results: Average-sized PM2.5 particles deposited on RGP contact lens and SCL surfaces after immersion in the PM2.5 solution were 3.1921.637 and 2.158 +/- 1.187/100m(2), respectively. On RGP lens surfaces, we observed both large (2.5 mu m diameter) and small (PM2.5) particles. PM2.5 particles were deposited in diffuse patterns, primarily along the honeycomb structural border of SCL, while no PM2.5 particles were found in the honeycomb hole of SCL surfaces. Washing in PBS removed the larger PM particles from RGP lens surfaces, but left copious amounts of PM2.5 particles. In contrast, nearly all PM particles were removed from SCL surfaces after PBS washing. OP values of RGP lens and SCL appeared to be unchanged by PM2.5 deposition. RI values increased in both RGP lens and SCL groups after PM2.5 deposition. However, these increases were not statistically significant, suggesting that PM2.5 deposition itself does not cause fluctuations in contact lens RI.Conclusions: Deposition of PM2.5 particles on contact lens surfaces varies according to lens material. PM2.5 particles deposited on SCL, but only large particles on RGP surfaces were able to be removed by washing in PBS and did not appear to alter OP and RI of either lens type.