GROWTH-CHARACTERISTICS OF GROUP-A STREPTOCOCCI IN A NEW CHEMICALLY DEFINED MEDIUM
GROWTH-CHARACTERISTICS OF GROUP-A STREPTOCOCCI IN A NEW CHEMICALLY DEFINED MEDIUM
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DOI：
10.1128/iai.27.2.444-448.1980
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发表时间：
1980-01-01
影响因子：
3.1
通讯作者：
KESSLER, RE
中科院分区：
文献类型：
--
作者：
VANDERIJN, I;KESSLER, RE
一种新的用于A组链球菌生长的化学定义的培养基已经被配制出来。这种新定义的培养基比以前描述的定义的培养基有以下优点：(I)20个菌株的生长速度(即倍增)与在复合培养基中的生长速度相当；(Ii)每个菌株在新定义的培养基中的生长密度都高于在复合培养基中的培养密度；(Iii)无需任何事先的适应方案，就可以从带有小接种量的复合培养基中转移；以及(Iv)在这种新的定义的培养基中生长的毒力因子(即M蛋白和透明质酸)和胞外酶的产生与在复合培养基中的相当。
A new chemically defined medium for the growth of group A streptococci has been formulated. The advantages of this new medium over previously described defined media are: (i) rates of growth (i.e., doubling times) of 20 strains were comparable to the rates of growth in complex media; (ii) each strain grew to a higher culture density in the new defined medium than in complex media; (iii) transfer from complex media with small inocula was possible without any prior adaptation regimen; and (iv) the production of virulence factors (i.e., M protein and hyaluronic acid) and extracellular enzymes during growth in this new medium was comparable to that in complex media.