A PROSPECTIVE-STUDY OF DELIRIUM IN HOSPITALIZED ELDERLY
A PROSPECTIVE-STUDY OF DELIRIUM IN HOSPITALIZED ELDERLY
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DOI：
10.1001/jama.263.8.1097
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发表时间：
1990-02-23
影响因子：
120.7
通讯作者：
KAPOOR, WN
中科院分区：
文献类型：
--
作者：
FRANCIS, J;MARTIN, D;KAPOOR, WN
对229例老年谵妄患者的患病率、危险因素及预后进行了研究。50例患者（22%）符合谵妄标准；无精神错乱的老年人为对照组。钠水平异常、疾病严重程度、痴呆、发烧或体温过低、精神活性药物使用和氮质血症与谵妄的风险相关。有三种或三种以上危险因素的患者谵妄发生率为60%。精神错乱患者住院时间为12.1天，对照组为7.2天，死亡（8%对1%）或住院（16%对3%）的可能性更大。疾病严重程度预测6个月死亡率，但谵妄的影响不显著。谵妄常见于住院老年人，与慢性和急性疾病有关，并表明老年人存在死亡、住院时间较长和住院的风险。与谵妄相关的死亡率增加似乎可以用更严重的疾病来解释。
The prevalence, risk factors, and outcomes of delirium were studied in 229 elderly patients. Fifty patients (22%) met criteria for delirium; nondelirious elderly constituted the control group. Abnormal sodium levels, illness severity, dementia, fever or hypothermia psychoactive drug use, and azotemia were associated with risk of delirium. Patients with three or more risk factors had a 60% rate of delirium. Delirious patients stayed 12.1 days in the hospital vs 7.2 days for controls and were more likely to die (8% vs 1%) or be institutionalized (16% vs 3%). Illness severity predicted 6-month mortality, but the effect of delirium was not significant. Delirium occurs commonly in hospitalized elderly, is associated with chronic and acute problems, and identifies elderly at risk for death, longer hospitalization, and institutionalization. The increased mortality associated with delirium appears to be explained by greater severity of illness.