Towards CARS endoscopy

Towards CARS endoscopy
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DOI:
10.1364/oe.14.004427
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发表时间:
2006-05-15
期刊:
影响因子:
3.8
通讯作者:
Xie, X. Sunney
Xie, X. Sunney
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Légaré, François;Evans, Conor L.;Xie, X. Sunney

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我们提供汽车内窥镜的原理验证演示。该设计使用单模光纤,其远端连接有聚焦单元。皮秒泵浦和斯托克斯脉冲串在近红外线通过光纤传递,几乎不变的光谱和时间特性的强度所需的内窥镜。通过收集样本处产生的epi-CARS信号并相对于光纤对样本进行光栅扫描来记录汽车内窥镜图像。这种汽车内窥镜原型代表了生物医学应用中原位化学选择性成像的重要一步。(c)2006年美国光学学会。
We provide a proof-of-principle demonstration of CARS endoscopy. The design utilizes a single mode optical fiber with a focusing unit attached to the distal end. Picosecond pump and Stokes pulse trains in the near infrared are delivered through the fiber with nearly unaltered spectral and temporal characteristics at intensities needed for endoscopy. CARS endoscopic images are recorded by collecting the epi-CARS signal generated at the sample and raster scanning the sample with respect to the fiber. This CARS endoscope prototype represents an important step towards in situ chemically selective imaging for biomedical applications. (c) 2006 Optical Society of America.