Fine Needle Aspiration Cytology Implementation and Malignancy Rates in Children and Adolescents Based on Japanese Guidelines: The Fukushima Health Management Survey
Fine Needle Aspiration Cytology Implementation and Malignancy Rates in Children and Adolescents Based on Japanese Guidelines: The Fukushima Health Management Survey
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DOI：
10.1089/thy.2021.0072
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发表时间：
2021-11-01
期刊：
影响因子：
6.6
通讯作者：
Kamiya, Kenji
中科院分区：
文献类型：
--
作者：
Shimura, Hiroki;Matsuzuka, Takashi;Kamiya, Kenji
背景资料：甲状腺超声检查（TUE）程序中启动的福岛县的居民年龄20毫米。结果：在PLBS和第一FSS，1362和1382例甲状腺结节直径1毫米，分别被发现。在直径为5.1-10.0、10.1-20.0和20.1 mm的结节中，PLBS中FNAC的执行率分别为20.1%、63.2%和87.7%。在第一次FSS中，直径为5.1 - 10.0、10.1-20.0和>= 20.1 mm的结节受试者的FNAC执行率分别为7.3%、26.0%和50.0%。在接受FNAC的受试者中，PLBS和首次FSS中恶性和疑似恶性结节的检出率分别为21.4%和34.1%。在第一个FSS，恶性或疑似恶性结节被发现在0.63%和0.40%的受试者谁有结节的直径= 10.0 mm的直径在PLBS，没有恶性肿瘤detected.Conclusions：使用的协议，符合日本指南导致FNAC的执行率降低，并在恶性肿瘤的检测率增加较小的结节。此外，使用该策略使我们能够避免>10.0 mm的甲状腺癌的检测失败。
Background: The thyroid ultrasound examination (TUE) program was initiated among the residents of Fukushima Prefecture aged 20 mm.Results: In the PLBS and the first FSS, 1362 and 1382 cases with thyroid nodules sized 1 mm in diameter were found, respectively. The implementation rates of FNAC in the PLBS were 20.1%, 63.2%, and 87.7% of subjects with nodules sized 5.1-10.0, 10.1-20.0, and 20.1 mm in diameter, respectively. In the first FSS, the FNAC implementation rates were 7.3%, 26.0%, and 50.0% in the subjects with nodules with diameters 5.110.0, 10.1-20.0, and >= 20.1 mm, respectively. In the subjects who underwent FNAC, the detection rates of malignant and suspected malignant nodules were 21.4% and 34.1% in the PLBS and first FSS, respectively. In the first FSS, malignant or suspected malignant nodules were found in 0.63% and 0.40% of subjects who had nodules of diameters = 10.0 mm in diameter in the PLBS, no malignancies were detected.Conclusions: The use of a protocol that conformed to the Japanese guidelines led to a reduction in the FNAC implementation rate and an increase in the malignancy detection rate in smaller nodules. In addition, the use of this strategy enabled us to avoid detection failure of thyroid carcinomas >10.0 mm.