Brain connectivity and psychiatric comorbidity in adolescents with Internet gaming disorder
Brain connectivity and psychiatric comorbidity in adolescents with Internet gaming disorder
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DOI：
10.1111/adb.12347
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发表时间：
2017-05-01
影响因子：
3.4
通讯作者：
Anderson, Jeffrey S.
中科院分区：
文献类型：
--
作者：
Han, Doug Hyun;Kim, Sun Mi;Anderson, Jeffrey S.
长时间玩网络视频游戏可能会对人类认知和大脑发育产生多重和复杂的影响，包括消极和积极的影响。目前还没有一个共识的原则影响的视频游戏玩既不对大脑发育，也不对关系到精神科comormalities。在这项研究中，78名患有网络游戏障碍（IGD）的青少年和73名没有IGD的对照受试者，包括没有其他精神共病、患有重度抑郁症和注意缺陷多动障碍（ADHD）的亚组，被纳入3 T静息状态功能磁共振成像分析。分别采用Young网络成瘾量表、Beck抑郁量表、Beck焦虑量表和韩国ADHD量表评估网络游戏障碍、抑郁、焦虑和ADHD症状的严重程度。IGD患者在7对区域之间显示出增加的功能相关性，根据多个统计检验，所有这些区域都满足q <0.05的错误发现率：左额叶眼区到背侧前扣带回，左额叶眼区到右前扣带回，左背外侧前额叶皮质（DLPFC）到左颞顶交界（TPJ），右DLPFC到右TPJ，右听觉皮质到右运动皮质，右侧听觉皮质至辅助运动区，右侧听觉皮质至背侧前扣带回。这些研究结果可能代表了延长游戏的训练效果，并表明游戏玩家的风险或倾向，过度连接的默认模式和执行控制网络，可能与精神共病。
Prolonged Internet video game play may have multiple and complex effects on human cognition and brain development in both negative and positive ways. There is not currently a consensus on the principle effects of video game play neither on brain development nor on the relationship to psychiatric comorbidity. In this study, 78 adolescents with Internet gaming disorder (IGD) and 73 comparison subjects without IGD, including subgroups with no other psychiatric comorbid disease, with major depressive disorder and with attention deficit hyperactivity disorder (ADHD), were included in a 3 T resting state functional magnetic resonance imaging analysis. The severity of Internet gaming disorder, depression, anxiety and ADHD symptoms were assessed with the Young Internet Addiction Scale, the Beck Depression Inventory, the Beck Anxiety Inventory and the Korean ADHD rating scales, respectively. Patients with IGD showed an increased functional correlation between seven pairs of regions, all satisfying q < 0.05 False discovery rates in light of multiple statistical tests: left frontal eye field to dorsal anterior cingulate, left frontal eye field to right anterior insula, left dorsolateral prefrontal cortex (DLPFC) to left temporoparietal junction (TPJ), right DLPFC to right TPJ, right auditory cortex to right motor cortex, right auditory cortex to supplementary motor area and right auditory cortex to dorsal anterior cingulate. These findings may represent a training effect of extended game play and suggest a risk or predisposition in game players for over-connectivity of the default mode and executive control networks that may relate to psychiatric comorbidity.