Pseudomonas aeruginosa bacteremia:: Risk factors for mortality and influence of delayed receipt of effective antimicrobial therapy on clinical outcome
Pseudomonas aeruginosa bacteremia:: Risk factors for mortality and influence of delayed receipt of effective antimicrobial therapy on clinical outcome
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DOI：
10.1086/377200
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发表时间：
2003-09-15
影响因子：
11.8
通讯作者：
Choe, KW
中科院分区：
文献类型：
--
作者：
Kang, CI;Kim, SH;Choe, KW
在医院感染的病原体中，铜绿假单胞菌被认为是致病和致死的主要原因。对136例铜绿假单胞菌菌血症患者的资料进行回顾性分析，以评估死亡的危险因素。患者的中位年龄为55岁（范围：15 - 85岁），78.7%的病例为医院获得性，30天死亡率为39%（53/136例患者）。多因素分析表明，死亡的危险因素包括严重脓毒症、肺炎、延迟开始有效的抗菌治疗和APACHE II评分增加（所有P值
Among the nosocomial pathogens, Pseudomonas aeruginosa is recognized as a major cause of morbidity and mortality. Data on 136 patients with P. aeruginosa bacteremia were retrospectively analyzed to evaluate risk factors for mortality. The median age of the patients was 55 years ( range, 15 - 85 years), 78.7% of the cases were hospital-acquired, and the 30-day mortality rate was 39% ( 53 of 136 patients). Multivariate analysis demonstrated that risk factors for mortality included severe sepsis, pneumonia, delay in starting effective antimicrobial therapy, and an increasing APACHE II score ( all P values