Room Temperature C-P Bond Formation Enabled by Merging Nickel Catalysis and Visible-Light-Induced Photoredox Catalysis
Room Temperature C-P Bond Formation Enabled by Merging Nickel Catalysis and Visible-Light-Induced Photoredox Catalysis
复制标题
通过合并镍催化和可见光诱导光氧化还原催化实现室温 C-P 键形成
DOI：
10.1002/chem.201500227
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Wen-Jing Xiao
中科院分区：
文献类型：
--
作者：
Jun Xuan;Ting-Ting Zeng;Jia-Rong Chen;Liang-Qiu Lu;Wen-Jing Xiao
将镍催化和可见光诱导的光氧化还原催化相结合，实现了二芳基氧化膦与芳基碘的新型高效C-P键形成反应.该双催化反应显示出宽的底物范围、优异的官能团耐受性，并且以良好至优异的产率提供相应的产物。与先前报道的在C = C键的构建中使用光氧化还原/镍双重催化相比，观察到本文所述的方法是第一个允许C-杂原子键形成的方法。
A novel and efficient CP bond formation reaction of diarylphosphine oxides with aryl iodides was achieved by combining nickel catalysis and visible‐light‐induced photoredox catalysis. This dual‐catalytic reaction showed a broad substrate scope, excellent functional group tolerance, and afforded the corresponding products in good to excellent yields. Compared with the previously reported use of photoredox/nickel dual catalysis in the construction of CC bonds, the methodology described herein was observed to be the first to allow for C‐heteroatom bond formation.