Parental vaccine hesitancy in Italy - Results from a national survey

Parental vaccine hesitancy in Italy - Results from a national survey
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DOI:
10.1016/j.vaccine.2017.12.074
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发表时间:
2018-02-01
期刊:
影响因子:
5.5
通讯作者:
Rota, Maria Cristina
Rota, Maria Cristina
中科院分区:
医学3区
文献类型:
--
作者:
Giambi, Cristina;Fabiani, Massimo;Rota, Maria Cristina

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在意大利,2016年,我们进行了一项横断面调查,以估计16-36个月儿童的父母对疫苗的犹豫不决,并调查其决定因素。父母对疫苗的态度和信念的数据是通过在线填写或在儿科医生办公室和托儿所自行填写的问卷收集的。根据孩子自己报告的破伤风和麻疹疫苗接种情况,父母被分为赞成疫苗接种、不愿接种疫苗或反对接种疫苗。采用多因素Logistic回归分析3130份调查问卷,结果表明:83.7%的家长支持疫苗接种,15.6%的家长不愿接种疫苗,0.7%的家长反对接种疫苗。安全问题是拒绝(38.1%)或中断(42.4%)疫苗接种的主要报告原因。反对接种疫苗和犹豫不决的父母对短期(85.7%和79.7%比60.4%)和长期(95.2%和72.3%比43.7%)疫苗不良反应的恐惧程度明显高于支持疫苗的父母。大多数支持接种疫苗的父母和犹豫不决的父母都同意接种疫苗的好处。大多数支持接种疫苗的父母和犹豫不决的父母(分别为96.9%和83.3%)认为家庭儿科医生是可靠的信息来源,而反对接种疫苗的父母认为家庭儿科医生是可靠的信息来源。与犹豫不决相关的主要因素是:没有收到儿科医生建议给他们的孩子全面接种疫苗[调整后的优势比(AOR):3.21,95%CI:2.14-4.79],对疫苗接种的意见不一致(AOR:1.64,95%CI:1.11-2.43),见过有严重不良反应的儿童的父母(AOR:1.49,95%CI:1.03-2.15),以及主要使用非传统药物治疗(AOR:2.05,疫苗安全性被认为是所有父母都关心的问题,尽管犹豫不决和反对接种疫苗的父母更是如此。与支持接种疫苗的父母类似,犹豫不决的父母认为接种疫苗是一种重要的预防工具,并信任他们的家庭儿科医生,这表明他们可以从适当的沟通干预中受益。按照国家建议,培训卫生专业人员并提供有关疫苗接种的统一信息,对于回应他们的关切至关重要。(C)2017爱思唯尔有限公司。保留所有权利。
In Italy, in 2016, we conducted a cross-sectional survey to estimate vaccine hesitancy and investigate its determinants among parents of children aged 16-36 months.Data on parental attitudes and beliefs about vaccinations were collected through a questionnaire administered online or self-administered at pediatricians' offices and nurseries. Parents were classified as pro-vaccine, vaccine-hesitant or anti-vaccine, according to self-reported tetanus and measles vaccination status of their child. Multivariable logistic regression was used to investigate factors associated with hesitancy.A total of 3130 questionnaires were analysed: 83.7% of parents were pro-vaccine, 15.6% vaccine hesitant and 0.7% anti-vaccine. Safety concerns are the main reported reason for refusing (38.1%) or interrupting (42.4%) vaccination. Anti-vaccine and hesitant parents are significantly more afraid than pro-vaccine parents of short-term (85.7 and 79.7% vs 60.4%) and long-term (95.2 and 72.3% vs 43.7%) vaccine adverse reactions. Most pro-vaccine and hesitant parents agree about the benefits of vaccinations. Family pediatricians are considered a reliable source of information by most pro-vaccine and hesitant parents (96.9 and 83.3% respectively), against 45% of anti-vaccine parents. The main factors associated with hesitancy were found to be: not having received from a paediatrician a recommendation to fully vaccinate their child [adjusted odds ratio (AOR): 3.21, 95% CI: 2.14-4.79], having received discordant opinions on vaccinations (AOR: 1.64, 95% CI: 1.11-2.43), having met parents of children who experienced serious adverse reactions (AOR: 1.49, 95% CI: 1.03-2.15), and mainly using non-traditional medical treatments (AOR: 2.05, 95% CI: 1.31-3.19).Vaccine safety is perceived as a concern by all parents, although more so by hesitant and anti-vaccine parents. Similarly to pro-vaccine parents, hesitant parents consider vaccination an important prevention tool and trust their family pediatricians, suggesting that they could benefit from appropriate communication interventions. Training health professionals and providing homogenous information about vaccinations, in line with national recommendations, are crucial for responding to their concerns. (C) 2017 Elsevier Ltd. All rights reserved.