Dynamics of neuronal responses in macaque MT and VIP during motion detection
Dynamics of neuronal responses in macaque MT and VIP during motion detection
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DOI：
10.1038/nn924
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发表时间：
2002-10-01
影响因子：
25
通讯作者：
Maunsell, JHR
中科院分区：
文献类型：
--
作者：
Cook, EP;Maunsell, JHR
我们研究了在运动检测任务中，神经元活动和行为之间的关系是如何随着时间的推移而演变的。我们记录了处理运动的两个视觉皮层区域，颞叶中部（MT）和腹侧顶叶内（VIP）区域，利用受试者检测运动刺激所需的时间来评估潜在神经元信号的动态。单神经元活动与刺激检测和反应时间（RT）相关。使用简单的阈值检测模型，两个地区的人口反应的上升边缘高度预测RT。然而，群体反应的时间过程在MT和VIP之间存在差异。对于MT，神经元反应的开始相对恒定，而对于VIP，神经元反应的开始随着rt而增加。与先前的研究相反，我们发现单个神经元在实际检测时间的限制下并不是运动信号的可靠检测器。
We examined how the relationship between neuronal activity and behavior evolved over time during a motion-detection task. Recording from two regions of visual cortex that process motion, the middle temporal (MT) and ventral intraparietal (VIP) areas, we used the time it took subjects to detect a motion stimulus to evaluate the dynamics of the underlying neuronal signals. Single-neuron activity was correlated with stimulus detection and reaction time (RT) in both areas. The rising edge of the population response from both areas was highly predictive of RT using a simple threshold-detection model. The time course of the population responses, however, differed between MT and VIP. For MT, the onset of the neuronal response was relatively constant, whereas for VIP the onset of the neuronal responses increased with RT. In contrast to previous studies, we found that single neurons were not reliable detectors of the motion signal when constrained by realistic detection times.