The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro.
The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro.
复制标题
DOI：
10.17912/micropub.biology.000546
复制
发表时间：
2022
影响因子：
--
通讯作者：
Ferkey, Denise M
中科院分区：
文献类型：
--
作者：
Bowitch, Alexander;Chinsky, Tyler M;Yu, Michael C;Ferkey, Denise M
线虫 OCTR-1 和人 ADRA2A 受体第三个细胞内环内的精氨酸在体外被人精氨酸甲基转移酶 PRMT5 甲基化。这些残基的甲基化可用于调节体内受体信号传导。
Arginines within the third intracellular loop of the C. elegans OCTR-1 and human ADRA2A receptors are methylated by the human protein arginine methyltransferase PRMT5 in vitro . Methylation of these residues could serve to modulate receptor signaling in vivo .