Activation of carbonyl compounds by double hydrogen bonding: An emerging tool in asymmetric catalysis
Activation of carbonyl compounds by double hydrogen bonding: An emerging tool in asymmetric catalysis
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DOI：
10.1002/anie.200301732
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发表时间：
2004-04-04
影响因子：
16.6
通讯作者：
Pihko, PM
中科院分区：
文献类型：
--
作者：
Pihko, PM
在开发用于羰基化学的新型手性催化剂中，一个特别有用的工具是通过双氢键活化羰基（参见方案）。一系列不同的反应，如不对称Diels-Alder反应、杂Diels-Alder反应、羟醛缩合反应和Morita-Baylis-Hillman反应，都可以通过这种双氢键催化剂来加速。
An exceptionally useful tool in the development of novel chiral catalysts for carbonyl chemistry is the activation of carbonyl groups by double hydrogen bonding (see scheme). A diverse set of reactions such as the asymmetric Diels–Alder, hetero‐Diels–Alder, aldol, and Morita–Baylis–Hillman reactions can be accelerated by such double‐hydrogen‐bonding catalysts.