Calculation of spherical red blood cell deformation in a dual-beam optical stretcher
Calculation of spherical red blood cell deformation in a dual-beam optical stretcher
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DOI：
10.1364/oe.15.016029
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发表时间：
2007-11-26
期刊：
影响因子：
3.8
通讯作者：
Chiou, Arthur
中科院分区：
文献类型：
--
作者：
Bareil, Paul B.;Sheng, Yunlong;Chiou, Arthur
本文提出了一种基于线弹性膜理论的数值方法，由细胞膜上的光子应力分布来计算球形细胞的形态变形。该方法适用于拟合的球形人红细胞的变形的实验数据捕获和拉伸的光纤双光束陷阱与一个单一的拟合参数Eh，其中E是杨氏弹性模量和h是细胞膜的厚度。我们得到Eh =（20 +/- 2）mu Nm（-1），这与先前报道的结果相当。这种数值方法可以应用于一般的实验条件。(c)2007年，美国光学学会。
We present a numerical method based on the linear elastic membrane theory to compute the morphological deformation of a spherical cell from the photonics stress distribution over the cellular membrane. The method is applied to fit the experimental data for deformation of a spherical human red blood cell trapped and stretched in a fiber-optical dual-beam trap with a single fitting parameter Eh where E is the Young's modulus of elasticity and h is the thickness of the cell membrane. We obtained Eh = (20 +/- 2)mu Nm(-1) which is comparable to results reported earlier. This numerical method can be applied in general experimental conditions. (c) 2007 Optical Society of America.